COVID-19 is a fatal, fast-spreading pandemic, and numerous attempts are being made
around the world to understand and manage the disease. COVID-19 patients may develop a …

Background: COVID-19, caused by SARS-CoV-2, is a potentially lethal, rapidly-expanding
pandemic and many efforts are being carried out worldwide to understand and control the …

We have previously hypothesized that pentoxifylline could be beneficial for the treatment of
COVID-19 given its potential to restore the immune response equilibrium, reduce the impact …

Support Care Cancer 1993; 1: 331-3. 6. Amvros' eva TV, Votiakov VI, Andreeva OT, Vladyko
GV, Nikolaeva SN, Orlova SV, et al. New properties of trental as an inhibitor of viral activity …

The outburst of inflammatory response and hypercoagulability are among the factors
contributing to increased mortality in severe COVID-19 cases. Pentoxifylline (PTX), a …

Pentoxifylline (PTX) is a phosphodiesterase inhibitor that increases cyclic adenosine
monophosphate levels, which in turn activate protein kinase, leading to a reduction in the …

COVID-19 pandemic presents an unprecedented challenge to identify effective drugs for
treatment. Despite multiple clinical trials using different agents, there is still a lack of specific …

As of March 2020, coronavirus disease 2019 (COVID-19) was declared as pandemic. Since
then, several studies were conducted to discover appropriate therapeutic management of …

Objective: Miltefosine is an anti-cancer drug used to treat leishmaniasis and deadly
opportunistic free-living amoeba and other deadly pathogenic microorganisms. Several …

Pentoxifylline (PTX) is a methylxanthine derivative that has been developed as an
immunomodulatory agent and an improvement of microcirculation. Osteoradionecrosis …