Apparent absence of atovaquone/proguanil resistance in 477 Plasmodium falciparum isolates from untreated French travellers
L Musset, B Pradines, D Parzy, R Durand… - Journal of …, 2006 - academic.oup.com
Objectives: We examined the atovaquone in vitro susceptibility and the cytochrome b (cytb)
gene polymorphism of African Plasmodium falciparum isolates during the first years of …
gene polymorphism of African Plasmodium falciparum isolates during the first years of …
First Case of Emergence of Atovaquone-Proguanil Resistance in Plasmodium falciparum during Treatment in a Traveler in Comoros
H Savini, H Bogreau, L Bertaux… - Antimicrobial agents …, 2008 - Am Soc Microbiol
The patient presented with fever 10 days after the end of his trip, and a diagnosis of
falciparum malaria was made. Treatment with atovaquone-proguanil was well tolerated …
falciparum malaria was made. Treatment with atovaquone-proguanil was well tolerated …
[HTML][HTML] First Case of Emergence of Atovaquone Resistance in Plasmodium falciparum during Second-Line Atovaquone-Proguanil Treatment in South America
E Legrand, M Demar, B Volney, MT Ekala… - Antimicrobial agents …, 2007 - Am Soc Microbiol
The atovaquone-proguanil combination (Malarone) has been introduced in French Guiana
for prophylaxis and second-line treatment for Plasmodium falciparum malaria in 2002. We …
for prophylaxis and second-line treatment for Plasmodium falciparum malaria in 2002. We …
Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe
O Wichmann, N Muehlberger, T Jelinek… - Journal of Infectious …, 2004 - academic.oup.com
Background. Two single-point mutations of the Plasmodium falciparum cytochrome b gene
(Tyr268Asn and Tyr268Ser) were recently reported in cases of atovaquone/proguanil …
(Tyr268Asn and Tyr268Ser) were recently reported in cases of atovaquone/proguanil …
Genetic Confirmation of Atovaquone-Proguanil–Resistant Plasmodium falciparum Malaria Acquired by a Nonimmune Traveler to East Africa
E Schwartz, S Bujanover, KC Kain - Clinical infectious diseases, 2003 - academic.oup.com
We report a case of atovaquone-proguanil–resistant Plasmodium falciparum malaria
acquired by a nonimmune traveler to Kenya. Recurrent parasitemia occurred 30 days after …
acquired by a nonimmune traveler to Kenya. Recurrent parasitemia occurred 30 days after …
Novel Mutation in Cytochrome B of Plasmodium falciparum in One of Two Atovaquone-Proguanil Treatment Failures in Travelers Returning From Same Site in …
MM Plucinski, CS Huber, S Akinyi… - Open forum …, 2014 - academic.oup.com
Abstract Background. Atovaquone-proguanil (AP) is the most commonly used treatment for
uncomplicated Plasmodium falciparum malaria in the United States. Apparent AP treatment …
uncomplicated Plasmodium falciparum malaria in the United States. Apparent AP treatment …
[HTML][HTML] In vitro atovaquone/proguanil susceptibility and characterization of the cytochrome b gene of Plasmodium falciparum from different endemic regions of …
R Khositnithikul, P Tan-Ariya, M Mungthin - Malaria Journal, 2008 - Springer
Abstract Background The emergence of Plasmodium falciparum resistant to most currently
used antimalarial drugs is the major problem in malaria control along the Thai-Myanmar and …
used antimalarial drugs is the major problem in malaria control along the Thai-Myanmar and …
[HTML][HTML] Detection of atovaquone-proguanil resistance conferring mutations in Plasmodium falciparum cytochrome b gene in Luanda, Angola
S Pimentel, F Nogueira, C Benchimol, V Quinhentos… - Malaria Journal, 2006 - Springer
Background The fixed dose combination atovaquone-proguanil is a recently introduced
antimalarial for treatment and prophylaxis of Plasmodium falciparum malaria. It is highly …
antimalarial for treatment and prophylaxis of Plasmodium falciparum malaria. It is highly …
[HTML][HTML] Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as …
B Schwöbel, M Alifrangis, A Salanti, T Jelinek - Malaria journal, 2003 - Springer
Abstract Background Resistance of Plasmodium falciparum to atovaquone in vitro and in
vivo has been associated to mutations in the parasite cytochrome b gene. Methods Cultures …
vivo has been associated to mutations in the parasite cytochrome b gene. Methods Cultures …
[HTML][HTML] Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa
Background In vitro and in vivo resistance of Plasmodium falciparum to atovaquone or
atovaquone-proguanil hydrochloride combination has been associated to two point …
atovaquone-proguanil hydrochloride combination has been associated to two point …