Abstract Pendrin (SLC26A4) is an electroneutral anion exchanger in which function-altering
mutations cause inherited forms of non-syndromic (DFNB4) and syndromic deafness …

Pendrin is a membrane transporter encoded by solute carrier family26A4 (SLC26A4).
Mutations in this gene are known to cause hearing loss, and recent data from animal studies …

The PDS gene encodes a transmembrane protein, known as pendrin, which functions as a
transporter of iodide and chloride. Mutations in this gene are responsible for Pendred …

Abstract SLC26A4/PDS mutations cause Pendred Syndrome and non-syndromic deafness.
but some aspects of function and regulation of the SLC26A4 polypeptide gene product …

Mutation of SLC26A4 is the most common cause of prelingual hearing loss in East Asia.
Patients with SLC26A4 mutations have variable phenotypes ranging from non‐syndromic …

Deleterious mutations of SLC26A4 cause Pendred syndrome (PS), an autosomal recessive
disorder comprising goitre and deafness with enlarged vestibular aqueducts (EVA), and …

Background Mutations in the SLC26A4 gene, which encodes the anion transporter, pendrin,
are a major cause of autosomal recessive non-syndromic hearing loss (NSHL) in some …

Objective Pendred syndrome (PS) is an autosomal recessive disorder characterised by
sensorineural hearing loss and thyroid dyshormonogenesis. It is caused by biallelic …

Objective To investigate the mutations in the SLC26A4 gene in a Chinese patient with
Pendred syndrome. Methods The diagnosis of Pendred syndrome was confirmed by the …

Pendrin is an anion exchanger whose mutations are known to cause hearing loss. However,
recent data support the linkage between pendrin expression and airway diseases, such as …