Intracellular bacterial pathogens often rely on their hosts for essential nutrients. Host cells, in
turn, attempt to limit nutrient availability, using starvation as a mechanism of innate immunity …

The interaction between pathogenic microorganisms and their hosts is regulated by
reciprocal survival strategies, including competition for essential nutrients. Though …

Apart from cancer, metabolic reprogramming is also prevalent in other diseases, such as
bacterial infections. Bacterial infections can affect a variety of cells, tissues, organs, and …

Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

Pathogens, including viruses, bacteria, fungi, and parasites, remodel the metabolism of their
host to acquire the nutrients they need to proliferate. Thus, host cells are often perceived as …

Mammalian innate immunity stimulates antigen‐specific immune responses and acts to
control infection prior to the onset of adaptive immunity. Some bacterial pathogens replicate …

Autophagy, which targets cellular constituents for degradation, is normally inhibited in
metabolically replete cells by the metabolic checkpoint kinase mTOR. Although autophagic …

Microbes exert a major impact on human health and disease by either promoting or
disrupting homeostasis, in the latter instance leading to the development of infectious …

The interaction between host and pathogen decidedly shapes the outcome of an infection,
thus understanding this interaction is critical to the treatment of a pathogen-induced …

Due to their chemical versatility, transition metals were incorporated as cofactors for several
basic metabolic pathways in living organisms. This same characteristic makes them …