[HTML][HTML] Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease

J Zhao, W Gao, X Cai, J Xu, D Zou, Z Li, B Hu… - Theranostics, 2019 - ncbi.nlm.nih.gov
The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel
disease (IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS …

Zero‐valence selenium‐enriched Prussian blue nanozymes reconstruct intestinal barrier against inflammatory bowel disease via inhibiting Ferroptosis and T cells …

D Zhu, H Wu, K Jiang, Y Xu, Z Miao… - Advanced Healthcare …, 2023 - Wiley Online Library
The structural disruption of mechanical barrier and dysfunction of immune barrier in
intestinal, are important factors, that aggravate inflammatory bowel disease (IBD). To tackle …

Prussian blue nanozyme with multienzyme activity reduces colitis in mice

J Zhao, X Cai, W Gao, L Zhang, D Zou… - … applied materials & …, 2018 - ACS Publications
The overproduction of reactive oxygen species (ROS) is central to the progression of
inflammatory bowel disease (IBD), which may be the potential therapeutic target. Prussian …

A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease

F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …

Oral metal‐free melanin nanozymes for natural and durable targeted treatment of inflammatory bowel disease (IBD)

Q Huang, Y Yang, Y Zhu, Q Chen, T Zhao, Z Xiao… - Small, 2023 - Wiley Online Library
Oral antioxidant nanozymes bring great promise for inflammatory bowel disease (IBD)
treatment. To efficiently eliminate reactive oxygen species (ROS), various metal‐based …

Mn3O4 Nanozyme for Inflammatory Bowel Disease Therapy

Y Cheng, C Cheng, J Yao, Y Yu, Y Liu… - Advanced …, 2021 - Wiley Online Library
Recently, reactive oxygen species (ROS) scavenging nanozymes have been developed as
natural enzyme alternatives to treat inflammatory bowel disease (IBD) as well as other …

Application of metal-based nanozymes in inflammatory disease: a review

R Li, X Hou, L Li, J Guo, W Jiang… - … in Bioengineering and …, 2022 - frontiersin.org
Reactive oxygen species (ROS) are metabolites of normal cells in organisms, and normal
levels of ROS in cells are essential for maintaining cell signaling and other intracellular …

Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy

Y Liu, Y Cheng, H Zhang, M Zhou, Y Yu, S Lin… - Science …, 2020 - science.org
Here, an integrated cascade nanozyme with a formulation of Pt@ PCN222-Mn is developed
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …

Oral nanozyme-engineered probiotics for the treatment of ulcerative colitis

H Zhao, Y Du, L Liu, Y Du, K Cui, P Yu, L Li… - Journal of Materials …, 2022 - pubs.rsc.org
Probiotic-based therapy for ulcerative colitis (UC) is a novel and promising approach that
has gained much popularity in recent years. However, probiotics may be easily captured …

Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease

Y Cao, K Cheng, M Yang, Z Deng, Y Ma, X Yan… - Journal of …, 2023 - Springer
Background Inflammatory bowel disease (IBD) is a chronic nonspecific disease with
unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a …