Breath carbonyl compounds as biomarkers of lung cancer

M Li, D Yang, G Brock, RJ Knipp, M Bousamra… - Lung Cancer, 2015 - Elsevier
Objective Lung cancer dysregulations impart oxidative stress which results in important
metabolic products in the form of volatile organic compounds (VOCs) in exhaled breath. The …

Target analysis of volatile organic compounds in exhaled breath for lung cancer discrimination from other pulmonary diseases and healthy persons

M Koureas, P Kirgou, G Amoutzias… - Metabolites, 2020 - mdpi.com
The aim of the present study was to investigate the ability of breath analysis to distinguish
lung cancer (LC) patients from patients with other respiratory diseases and healthy people …

Detection of lung cancer with volatile markers in the breath

M Phillips, RN Cataneo, ARC Cummin, AJ Gagliardi… - Chest, 2003 - Elsevier
Study objectives To evaluate volatile organic compounds (VOCs) in the breath as tumor
markers in lung cancer. Alkanes and monomethylated alkanes are oxidative stress products …

[HTML][HTML] Predictive performance of selected breath volatile organic carbon compounds in stage 1 lung cancer

E Smirnova, C Mallow, J Muschelli, Y Shao… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Lung cancer remains the leading cause of cancer deaths accounting for almost
25% of all cancer deaths. Breath-based volatile organic compounds (VOCs) have been …

Exploring volatile organic compounds in breath for high-accuracy prediction of lung cancer

PH Tsou, ZL Lin, YC Pan, HC Yang, CJ Chang… - Cancers, 2021 - mdpi.com
Simple Summary Human-exhaled volatile organic compounds (VOCs) can be altered by
lung cancer and become identifiable biomarkers. We used selected ion flow tube mass …

Multigroup prediction in lung cancer patients and comparative controls using signature of volatile organic compounds in breath samples

SN Rai, S Das, J Pan, DC Mishra, XA Fu - Plos one, 2022 - journals.plos.org
Early detection of lung cancer is a crucial factor for increasing its survival rates among the
detected patients. The presence of carbonyl volatile organic compounds (VOCs) in exhaled …

[HTML][HTML] High sensitivity for lung cancer detection using analysis of exhaled carbonyl compounds

EM Schumer, JR Trivedi, V Van Berkel… - The Journal of thoracic …, 2015 - Elsevier
Objective Several volatile carbonyl compounds in exhaled breath have been identified as
cancer-specific markers. The potential for these markers to serve as a screening test for lung …

Calculated indices of volatile organic compounds (VOCs) in exhalation for lung cancer screening and early detection

X Chen, KG Muhammad, C Madeeha, W Fu, L Xu, Y Hu… - Lung Cancer, 2021 - Elsevier
Background Breath analysis is a promising noninvasive technique that offers a wide range
of opportunities to facilitate early diagnosis of lung cancer (LC). Method Exhaled breath …

The analysis of volatile organic compounds biomarkers for lung cancer in exhaled breath, tissues and cell lines

Y Wang, Y Hu, D Wang, K Yu, L Wang… - Cancer …, 2012 - content.iospress.com
Background: Volatile organic compounds (VOCs) biomarkers in breath provide a novel,
noninvasive and quick approach to diagnosis lung cancer. The aim of the proposed study …

Prediction of lung cancer using volatile biomarkers in breath

M Phillips, N Altorki, JHM Austin… - Cancer …, 2007 - content.iospress.com
Background: Normal metabolism generates several volatile organic compounds (VOCs) that
are excreted in the breath (eg alkanes). In patients with lung cancer, induction of high-risk …