Metered dose inhaler salbutamol treatment of asthma in the ED: comparison of two doses with plasma levels

G Rodrigo, C Rodrigo - The American journal of emergency medicine, 1996 - Elsevier
Two cumulative doses of salbutamol delivered by metered dose inhaler (MDI) with a pear-
shaped spacer were compared (400 μg vs 600 μg at 10-minute intervals). Twenty-two …

A new spacer device for administration of inhaled salbutamol: use in elderly asthmatics.

L Donateo, R Gerardi, L Cantini - Advances in Therapy, 1996 - europepmc.org
This randomized, parallel-group study compared the use of a metered-dose inhaler (MDI)
equipped with a new spacer device (Jet spacer) with that of a standard actuator in the …

Effects of airway calibre on lung delivery of nebulised salbutamol.

BJ Lipworth, DJ Clark - Thorax, 1997 - thorax.bmj.com
BACKGROUND: A study was undertaken to test the hypothesis that airway calibre may alter
lung deposition and therefore lung bioavailability of inhaled drugs as a result of narrowed …

Continuous nebulization of albuterol (salbutamol) in acute asthma

A Colacone, N Wolkove, E Stern, M Afilalo… - Chest, 1990 - Elsevier
We studied the safety and efficacy of albuterol (salbutamol) delivered by continuous
nebulization (CN) in the initial emergency department treatment of asthma. In a randomized …

Dose response to inhaled salbutamol in chronic obstructive airways disease

C Teale, JFJ Morrison, RL Page… - Postgraduate medical …, 1991 - academic.oup.com
High dose inhaled salbutamol is increasingly used in the management of chronic obstructive
airways disease. To determine the range of doses to achieve optimal bronchodilatation and …

Clinical trial of two inhalation techniques for pressurized aerosols

J Stauder, KG Hidinger - Journal of International Medical …, 1980 - journals.sagepub.com
The clinical effects of a bronchodilator, terbutaline sulphate, were compared after
administration in the beginning of the inhalation by means of a standard inhaler and …

Nebulizers or pressurized metered-dose inhalers in the treatment of asthma exacerbations.

D Radzik, DG Peroni… - Allergy & Asthma …, 2005 - search.ebscohost.com
The use of inhaled β< sub> 2-agonists delivered by a metered-dose inhaler (MDI) with a
holding chamber (spacer) actually is considered the best treatment for childhood acute …

Comparison of the effects of sequential or simultaneous administration of salbutamol and beclomethasone dipropionate

GM Pover, G Greger, P Kaspar - Respiration, 1986 - karger.com
The effect of the simultaneous administration of salbutamol and beclomethasone
dipropionate, from a combination inhaler, was compared with the same doses given with an …

Intravenous salbutamol and aminophylline in asthma: a search for synergy.

PD Handslip, AM Dart, BH Davies - Thorax, 1981 - thorax.bmj.com
The bronchodilation produced by increasing intravenous doses of aminophylline,
salbutamol, and a combination of aminophylline and salbutamol given in random order was …

Comparison of two dosage regimens of albuterol in acute asthma

ER McFadden Jr, L Strauss, R Hejal, G Galan… - The American journal of …, 1998 - Elsevier
Background: The standard therapy for acute episodes of asthma in the United States
consists of three 2.5-mg doses of aerosolized albuterol given every 20 minutes. Whether this …