Normalization of fat accrual in lipoatrophic, HIV-infected children switched from stavudine to tenofovir and from protease inhibitor to efavirenz
A Viganò, P Brambilla, L Cafarelli… - Antiviral …, 2007 - journals.sagepub.com
Objective An antiretroviral regimen based on lamivudine+ stavudine+ protease inhibitor
impairs peripheral fat accrual in HIV-infected children and adolescents. We assess the effect …
impairs peripheral fat accrual in HIV-infected children and adolescents. We assess the effect …
Severe insulin resistance contrasting with mild anthropometric changes in the adipose tissue of HIV-infected children with lipohypertrophy
M Beregszaszi, D Jaquet, M Levine… - International journal of …, 2003 - nature.com
BACKGROUND: The HIV-associated lipodystrophic syndrome (HIV-LDS) combines
redistribution of fat mass with insulin resistance and hyperlipidemia. We have previously …
redistribution of fat mass with insulin resistance and hyperlipidemia. We have previously …
Increased expression of TNF-α, IL-6, and IL-8 in HALS: implications for reduced adiponectin expression and plasma levels
AS Lihn, B Richelsen, SB Pedersen… - American Journal …, 2003 - journals.physiology.org
Human immunodeficiency virus (HIV)-associated lipodystrophy syndrome (HALS) is a side
effect of highly active antiretroviral therapy of HIV-infected patients; however, the mechanism …
effect of highly active antiretroviral therapy of HIV-infected patients; however, the mechanism …
Reduced adipogenic gene expression in thigh adipose tissue precedes human immunodeficiency virus-associated lipoatrophy
M Kratz, JQ Purnell, PA Breen… - The Journal of …, 2008 - academic.oup.com
Context: The expression of adipogenic genes in sc adipose tissue has been reported to be
lower among patients with HIV-associated lipoatrophy than HIV-uninfected controls. It is …
lower among patients with HIV-associated lipoatrophy than HIV-uninfected controls. It is …
Adipocyte-derived hormone levels in HIV lipodystrophy
L Kosmiski, D Kuritzkes, K Lichtenstein… - Antiviral …, 2003 - journals.sagepub.com
Objective Despite evidence for the role of adipocyte-derived hormones in insulin resistance,
little is known about their levels in human lipodystrophic states. We examined the …
little is known about their levels in human lipodystrophic states. We examined the …
Body fat abnormality in HIV-infected children and adolescents living in Europe: prevalence and risk factors
N Alam, M Cortina-Borja, T Goetghebuer… - JAIDS Journal of …, 2012 - journals.lww.com
Objectives: To estimate the prevalence of and identify risk factors for lipodystrophy syndrome
(LS) and body fat abnormality in a population of HIV-infected children and adolescents …
(LS) and body fat abnormality in a population of HIV-infected children and adolescents …
A rosiglitazone-induced increase in adiponectin does not improve glucose metabolism in HIV-infected patients with overt lipoatrophy
RME Blümer, M van der Valk… - American Journal …, 2009 - journals.physiology.org
HIV-infected patients on antiretroviral therapy frequently develop changes in body fat
distribution and disturbances in glucose metabolism, associated with reduced adiponectin …
distribution and disturbances in glucose metabolism, associated with reduced adiponectin …
Clinical features and management of non-HIV–related lipodystrophy in children: a systematic review
Context: Lipodystrophy syndromes are characterized by generalized or partial absence of
adipose tissue. Objective: We conducted a systematic review to synthesize data on clinical …
adipose tissue. Objective: We conducted a systematic review to synthesize data on clinical …
Circulating sex hormones and gene expression of subcutaneous adipose tissue oestrogen and alpha‐adrenergic receptors in HIV‐lipodystrophy: implications for fat …
O Andersen, SB Pedersen, B Svenstrup… - Clinical …, 2007 - Wiley Online Library
Objective Circulating oestradiol and testosterone, which have been shown to increase in
human immunodeficiency virus (HIV)‐infected patients following highly active antiretroviral …
human immunodeficiency virus (HIV)‐infected patients following highly active antiretroviral …
Relationship of fat distribution with adipokines in human immunodeficiency virus infection
LA Kosmiski, P Bacchetti, DP Kotler… - The Journal of …, 2008 - academic.oup.com
Background and Methods: HIV-infected patients receiving antiretroviral therapy often
develop changes in body fat distribution; the dominant change is reduction in sc adipose …
develop changes in body fat distribution; the dominant change is reduction in sc adipose …