Hydrogel containing dexamethasone-loaded nanocapsules for cutaneous administration: preparation, characterization, and in vitro drug release study

ML Marchiori, G Lubini, G Dalla Nora… - Drug development …, 2010 - Taylor & Francis
Context: Our group previously reported the development of dexamethasone-loaded
polymeric nanocapsules as an alternative for topical dermatological treatments. Objective …

Cationic polymeric nanocapsules as a strategy to target dexamethasone to viable epidermis: skin penetration and permeation studies

TC Beber, DF de Andrade… - … of Nanoscience and …, 2016 - ingentaconnect.com
The present work aimed to evaluate the behavior of dexamethasone-loaded cationic
polymeric nanocapsules in hydrogels, regarding their in vitro drug release and skin drug …

Nanoemulgel for improved topical delivery of desonide: Formulation design and characterization

Q Ma, J Zhang, B Lu, H Lin, R Sarkar, T Wu, X Li - AAPS PharmSciTech, 2021 - Springer
This research aimed to develop a novel drug delivery system to improve treatment of skin
disorders. The system is comprised of a Carbopol 980-based nanoemulgel (NE-gel) …

Nanoemulsion based hydrogel containing omega 3 fatty acids as a surrogate of betamethasone dipropionate for topical delivery

S Sharma, A Kumar, JK Sahni, J Ali… - Advanced Science …, 2012 - ingentaconnect.com
The aim of the present study was to investigate the potential of nanoemulsion formulation for
topical delivery of betamethasone dipropionate (BD) using fish oil (containing omega-3 fatty …

[HTML][HTML] Polymeric nanoparticles based topical gel of poorly soluble drug: formulation, ex-vivo and in vivo evaluation

M Elmowafy, A Samy, AE Abdelaziz, K Shalaby… - Beni-Suef University …, 2017 - Elsevier
The study was conducted to evaluate the potential application of nanocapsules and
nanospheres as topical drug delivery systems for indomethacin (as model drug). Both were …

Formulation and comparative in vitro evaluation of various dexamethasone-loaded pH-sensitive polymeric nanoparticles intended for dermal applications

FF Sahle, C Gerecke, B Kleuser, R Bodmeier - International journal of …, 2017 - Elsevier
Abstract pH-sensitive nanoparticles have a great potential for dermal and transfollicular drug
delivery. In this study, pH-sensitive, dexamethasone-loaded Eudragit® L 100, Eudragit® L …

[HTML][HTML] Rapidly dissolving microneedles for the delivery of steroid-loaded nanoparticles intended for the treatment of inflammatory skin diseases

H Dawud, A Abu Ammar - Pharmaceutics, 2023 - mdpi.com
Drug delivery through the skin has immense advantages compared to other routes of
administration and offers an optimal way to treat inflammatory skin diseases, where …

Locust bean gum-based hydrogel containing nanocapsules for 3, 3′-diindolylmethane delivery in skin inflammatory conditions

LM Giuliani, NS Pegoraro, C Camponogara… - Journal of Drug Delivery …, 2022 - Elsevier
A hydrogel based on polymeric nanocapsules containing 3, 3′-diindolmethane (DIM) was
developed for the treatment of skin inflammatory disorders. Nanocapsule suspensions were …

Improved efficacy in the treatment of contact dermatitis in rats by a dermatological nanomedicine containing clobetasol propionate

MC Fontana, JFP Rezer, K Coradini, DBR Leal… - European Journal of …, 2011 - Elsevier
We developed a dermatological nanomedicine containing clobetasol propionate-loaded
nanocapsules and evaluated its efficacy in a model of contact dermatitis after topical …

Nanoencapsulation potentiates the cutaneous anti-inflammatory effect of p, p′-methoxyl-diphenyl diselenide: Design, permeation, and in vivo studies of a …

MHM Sari, BCW Fulco, LM Ferreira… - European Journal of …, 2020 - Elsevier
This study aimed to investigate the feasibility of preparing a hydrogel based on (OMePhSe)
2-loaded poly (Ɛ-caprolactone) nanocapsules using carrageenan gum as a gel-forming …