An estimated 1.5% of the adult population in the United Kingdom has active chronic otitis
media with perforated tympanic membranes; this is comparable to the prevalence in western …

A discharging ear is a very common condition for the general practitioner and the ENT
surgeon. Oral and intravenous antibiotics have potential complications, are costly, and …

Clin. Otolaryngol. 2012, 37, 261–270 Objective: Primary: to compare one‐off administration
of boric acid powder with courses of 1% acetic acid and ciprofloxacin eardrops in treating …

Aminoglycoside antibiotics are widely used for the treatment of Gram negative sepsis. It is
well known that they can cause dose related renal toxicity and ototoxicity, which occur in …

In chronic otitis, the use of ear drops has certain advantages over the use of systemic
antibiotics. The choice of ear drop depends on the condition of the eardrum, microbial …

Reason for posting: Gentamicin ear drops can cause serious side effects (eg, vertigo,
imbalance, ataxia, oscillating vision, hearing loss and tinnitus) when used by patients with …

Until recently the only available antibiotic eardrops for treatment of the discharging middle
ear and mastoid cavity have been potentially ototoxic. With the advent of non‐ototoxic …

An electronic search of the literature was performed for reported cases of ototoxicity
associated with the use of topical antibiotic ear drops in humans. The dosage, duration, and …

Objective: The objective of this clinical trial was to asses the e1ficacy of topical quinolones
and compare it with the most commonly used aminoglycoside (gentamicin hydrocortisone) …

Objective: This systematic review aimed to establish that quinolones are as effective as
aminoglycosides when used to treat chronic suppurative otitis media. Method: The review …