Concomitant use of mesenchymal stem cells and neural stem cells for treatment of spinal cord injury: a combo cell therapy approach

SM Hosseini, M Sani, KH Haider, M Dorvash… - Neuroscience …, 2018 - Elsevier
Abstract Treatment: with neural stem cells (NSCs) provides a hope to recover the neural
damage and compensate for the lost neural structures for restoration of interrupted neural …

Neural stem cell-conditioned medium suppresses inflammation and promotes spinal cord injury recovery

Z Cheng, DB Bosco, L Sun, X Chen, Y Xu… - Cell …, 2017 - journals.sagepub.com
Spinal cord injury (SCI) causes functional impairment as a result of the initial injury followed
by secondary injury mechanism. SCI provokes an inflammatory response that causes …

[HTML][HTML] Multiple strategies enhance the efficacy of MSCs transplantation for spinal cord injury

QM Pang, KQ Deng, M Zhang, XC Wu, RL Yang… - Biomedicine & …, 2023 - Elsevier
Spinal cord injury (SCI) is a serious complication of the central nervous system (CNS) after
spine injury, often resulting in severe sensory, motor, and autonomic dysfunction below the …

[HTML][HTML] Current concepts of neural stem/progenitor cell therapy for chronic spinal cord injury

H Suzuki, Y Imajo, M Funaba, N Nishida… - Frontiers in Cellular …, 2022 - frontiersin.org
Chronic spinal cord injury (SCI) is a devastating condition that results in major neurological
deficits and social burden. It continues to be managed symptomatically, and no real …

Review of transplantation of neural stem/progenitor cells for spinal cord injury

AJ Mothe, CH Tator - International Journal of Developmental Neuroscience, 2013 - Elsevier
Spinal cord injury (SCI) is a debilitating condition often resulting in paralysis, yet currently
there is no effective treatment. Stem cell transplantation is a promising therapeutic strategy …

Strategies for effective neural circuit reconstruction after spinal cord injury: use of stem cells and biomaterials

Y Hou, X Liu, Y Guo, D Liu, P Guo, J Liu - World Neurosurgery, 2022 - Elsevier
Spinal cord injury (SCI) is a serious disease of the central nervous system, often with
irreversible loss of motor or sensory functions. Failure of axon connection and inhibition of …

[HTML][HTML] Mesenchymal stem cells and the neuronal microenvironment in the area of spinal cord injury

YO Mukhamedshina, OA Gracheva… - Neural regeneration …, 2019 - journals.lww.com
Cell-based technologies are used as a therapeutic strategy in spinal cord injury (SCI).
Mesenchymal stem cells (MSCs), which secrete various neurotrophic factors and cytokines …

Cell therapy augments functional recovery subsequent to spinal cord injury under experimental conditions

V Sabapathy, G Tharion, S Kumar - Stem Cells International, 2015 - Wiley Online Library
The spinal cord injury leads to enervation of normal tissue homeostasis ultimately leading to
paralysis. Until now there is no proper cure for the treatment of spinal cord injury. Recently …

[HTML][HTML] Multimodal repair of spinal cord injury with mesenchymal stem cells

Y Ma, Q Liang, Y Ding, I Han, X Zeng - Neurospine, 2022 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) is a result of a devastating injury to the central nervous system.
Currently, there is no effective treatment available for these patients. The possible use of …

[HTML][HTML] Filling the gap: neural stem cells as a promising therapy for spinal cord injury

IM Pereira, A Marote, AJ Salgado, NA Silva - Pharmaceuticals, 2019 - mdpi.com
Spinal cord injury (SCI) can lead to severe motor, sensory and social impairments having a
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …