The vast majority of children with sickle cell anemia (SCA) live in Africa, where evidence‐
based guidelines for primary stroke prevention are lacking. In Kano, Nigeria, we conducted …

Objectives. The prevalence of stroke among children with sickle cell disease (SCD) in sub-
Saharan Africa was systematically reviewed. Methods. Comprehensive searches of …

Sickle cell disease (SCD) is a hemoglobinopathy and a life-long blood disorder
characterized by red blood cells that assume an abnormal, rigid, sickle shape, which …

Homozygous sickle cell anaemia (SCA) is an inherited red blood cell disorder in which
haemoglobin A is replaced by haemoglobin S. The disease exhibits a wide spectrum of …

Background: Sickle cell anemia (SCA) is prevalent in Sudan in general, and in particular in
the western part of the country among Misseria tribe. School absence, depressive …

Background Cognitive impairment is a major neurological complication of sickle cell anemia
(SCA) in the United States, but there are limited studies of cognitive impairment in Nigeria …

Sickle cell disease is an inherited hemoglobinopathy associated with significant morbidity
and mortality. Reports suggest a high sickle cell disease burden among the indigenous …

Sickle cell anemia (SCA) is an autosomal recessive monogenic disease with significant
clinical variability. Cerebrovascular disease, particularly ischemic stroke, is one of the most …

Background Stroke is a major complication of sickle cell anaemia (SCA). It occurs commonly
in childhood with about 10% of children with sickle cell anaemia getting affected by this …

In Africa, sickle cell disease (SCD) is a major public health problem with over 200,000
babies born per year. In Ghana, approximately 15,000 (2%) of Ghanaian newborns are …