Non‐invasive microanalytical methods have been devised to study the energy metabolism
of single human preimplantation embryos. Psyruvate, which is added routinely to all media …

Embryo metabolism during early pregnancy has been investigated, mainly in the mouse and
rabbit, using a variety of catabolic and anabolic parameters. The rate of metabolic activity of …

The consumption of pyruvate and glucose and the production of lactate by 40 single human
preimplantation embryos has been measured using a non-invasive technique. Twelve of the …

The method for estimation of metabolic turnover by a single embryo at each stage of
preimplantation development is based on the incubation of an embryo in the presence of …

Pyruvate and glucose uptake by 73 indivudial human oocytes and preimplantation embryos
was measured non-invasively, using an ultramicrofluorescence assay to analyse changes in …

A method was developed to measure the activities of enzymes in extracts from single human
preimplantation embryos. The method permits the analysis of two enzymes plus appropriate …

During preimplantation human embryo development there is an increase in the synthesis of
macromolecules and a demand for energy. Consequently, the metabolic requirements of the …

Glucose turnover, as measured by CO 2 production, lactate accumulation and carbon
incorporation from [U-14 C] glucose as sole energy substrate, was low on the 2nd day of …

Although mammalian embryo development may be considered strictly to begin with the
formation of an oocyte, and progresses through implantation, organogenesis, and fetal …

The preimplantation mammalian embryo offers many unique research opportunities. Among
these is the possibility of studying the progression of metabolic systems during the transition …