[HTML][HTML] YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m6A-dependent manner

Y Lin, X Jin, Q Nie, M Chen, W Guo… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background The YTH domain family protein 3 (YTHDF3) is an important N6-
methyladenosine (m 6 A) reader which is involved in multiple cancers. However, the …

YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner

H Chen, Y Yu, M Yang, H Huang, S Ma, J Hu, Z Xi… - Cell & bioscience, 2022 - Springer
Abstract Background N6-methyladenosine (m6A) is the most common post-transcriptional
modification at the RNA level. However, the exact molecular mechanisms of m6A epigenetic …

YTHDF2 inhibits the migration and invasion of lung adenocarcinoma by negatively regulating the FAM83D-TGFβ1-SMAD2/3 pathway

T Zhao, M Wang, X Zhao, S Weng, K Qian, K Shi… - Frontiers in …, 2022 - frontiersin.org
Objective YTH domain family 2 (YTHDF2) is an important N6-methyladenosine (m6A)
reader, but its role in lung adenocarcinoma remains elusive. This study assessed its function …

m6A binding protein YTHDF2 in cancer

X Chen, X Zhou, X Wang - Experimental hematology & oncology, 2022 - Springer
YT521-B homology domain family member 2 (YTHDF2) is an N6-methyladenosine (m6A)-
binding protein that was originally found to regulate the stability of mRNA. Growing evidence …

YTHDF1 upregulation mediates hypoxia-dependent breast cancer growth and metastasis through regulating PKM2 to affect glycolysis

X Yao, W Li, L Li, M Li, Y Zhao, D Fang, X Zeng… - Cell death & …, 2022 - nature.com
N6-methyladenosine modification is the most common RNA modification mechanism in
mammals. YTHDF1, a m6A reader, can recognize the m6A of mRNAs to facilitate the …

YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition

X Luo, M Cao, F Gao, X He - Experimental hematology & oncology, 2021 - Springer
Abstract Background N 6-methyladenosine (m6A) modification, as the most abundant RNA
modification, widely participates in the physiological process and is involved in multiple …

YTHDF2 exerts tumor-suppressor roles in gastric cancer via up-regulating PPP2CA independently of m6A modification

Y Zhou, K Fan, N Dou, L Li, J Wang, J Chen… - Biological procedures …, 2023 - Springer
Background YTHDF2 is one of important readers of N6-methyladenosine (m6A) modification
on RNA. Growing evidence implicates that YTHDF2 takes an indispensable part in the …

[HTML][HTML] RNA N6-methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer

B Tan, K Zhou, W Liu, E Prince, Y Qing, Y Li, L Han… - Theranostics, 2022 - ncbi.nlm.nih.gov
Abstract RNA N 6-methyladenosine (m 6 A) modification and its regulators fine tune gene
expression and contribute to tumorigenesis. This study aims to uncover the essential role …

[PDF][PDF] RETRACTED: YTHDF1 facilitates the progression of hepatocellular carcinoma by promoting FZD5 mRNA translation in an m6A-dependent manner

X Liu, J Qin, T Gao, C Li, B He, B Pan, X Xu… - … Therapy-Nucleic Acids, 2020 - cell.com
Hepatocellular carcinoma (HCC), one of the most aggressive malignancies, ranks as the
fourth leading cause of cancerrelated deaths worldwide. Emerging evidence indicates that …

Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis

P Xu, K Hu, P Zhang, ZG Sun, N Zhang - Cancer Cell International, 2022 - Springer
Abstract Background N6-methyladenosine (m6A) is a dynamic and reversible internal RNA
structure of eukaryotic mRNA. YTH domain family 2 (YTHDF2), an m6A-specific reader YTH …