A place for host–microbe symbiosis in the comparative physiologist's toolbox

KD Kohl, HV Carey - Journal of Experimental Biology, 2016 - journals.biologists.com
Although scientists have long appreciated that metazoans evolved in a microbial world, we
are just beginning to appreciate the profound impact that host-associated microbes have on …

Microbiomes as sources of emergent host phenotypes

JB Lynch, EY Hsiao - Science, 2019 - science.org
Microbial communities associated with animals exert powerful influences on host
physiology, regulating metabolism and immune function, as well as complex host behaviors …

Simple animal models for microbiome research

AE Douglas - Nature Reviews Microbiology, 2019 - nature.com
The health and fitness of animals, including humans, are influenced by the presence and
composition of resident microbial communities. The development of rational microbial …

[HTML][HTML] Experimental evolution as an underutilized tool for studying beneficial animal–microbe interactions

KL Hoang, LT Morran, NM Gerardo - Frontiers in microbiology, 2016 - frontiersin.org
Microorganisms play a significant role in the evolution and functioning of the eukaryotes with
which they interact. Much of our understanding of beneficial host–microbe interactions stems …

Exploring host–microbiota interactions in animal models and humans

AD Kostic, MR Howitt, WS Garrett - Genes & development, 2013 - genesdev.cshlp.org
The animal and bacterial kingdoms have coevolved and coadapted in response to
environmental selective pressures over hundreds of millions of years. The meta'omics …

[HTML][HTML] Which experimental systems should we use for human microbiome science?

AE Douglas - PLoS biology, 2018 - journals.plos.org
Microbiome science is revealing that the phenotype and health of animals, including
humans, depend on the sustained function of their resident microorganisms. In this essay, I …

[HTML][HTML] Behavioral microbiomics: a multi-dimensional approach to microbial influence on behavior

ACN Wong, A Holmes, F Ponton, M Lihoreau… - Frontiers in …, 2015 - frontiersin.org
The role of microbes as a part of animal systems has historically been an under-appreciated
aspect of animal life histories. Recently, evidence has emerged that microbes have wide …

Microbiomes In Natura: Importance of Invertebrates in Understanding the Natural Variety of Animal-Microbe Interactions

JM Petersen, J Osvatic - Msystems, 2018 - Am Soc Microbiol
Animals evolved in a world teeming with microbes, which play pivotal roles in their health,
development, and evolution. Although the overwhelming majority of living animals are …

[HTML][HTML] Microbial underdogs: exploring the significance of low-abundance commensals in host-microbe interactions

G Han, S Vaishnava - Experimental & Molecular Medicine, 2023 - nature.com
Our understanding of host-microbe interactions has broadened through numerous studies
over the past decades. However, most investigations primarily focus on the dominant …

Links between natural variation in the microbiome and host fitness in wild mammals

TA Suzuki - Integrative and comparative biology, 2017 - academic.oup.com
Recent studies in model organisms have shown that compositional variation in the
microbiome can affect a variety of host phenotypes including those related to digestion …