Prediction of Potential Drug Targets and Vaccine Candidates Against Antibiotic-Resistant Pseudomonas aeruginosa

FS Shamsinejad, Z Zafari - International Journal of Peptide Research and …, 2022 - Springer
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections,
characterized by increasing antibiotic resistance, severity and mortality. Therefore …

In silico Identification of Novel Therapeutic Targets and Epitopes among the Essential Hypothetical Protein of Pseudomonas aeruginosa: A Novel Approach for …

B Atron, Z Yousif - 2023 - researchsquare.com
Background. Pseudomonas aeruginosa is a critical pathogen that represents a challenge in
healthcare due to its virulence and antibiotic resistance capabilities. The development of …

Quest for Novel Preventive and Therapeutic Options Against Multidrug-Resistant Pseudomonas aeruginosa

S Irum, S Andleeb, A Ali, MI Rashid, M Majid - International Journal of …, 2021 - Springer
Pseudomonas aeruginosa (P. aeruginosa) is a critical healthcare challenge due to its ability
to cause persistent infections and the acquisition of antibiotic resistance mechanisms. Lack …

Bioinformatics analyses for the designation of a hybrid protein against urinary tract infections caused by Pseudomonas aeruginosa and investigation of the presence …

H Sharbatdaralaei, MR Asadi Karam… - Journal of …, 2022 - Taylor & Francis
Pseudomonas aeruginosa is an important pathogen causing urinary tract infections (UTIs)
and resistance to antibiotics has increased the need for a vaccine against this bacterium. P …

In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii

E Zadeh Hosseingholi, G Zarrini… - Microbial Drug …, 2020 - liebertpub.com
Acinetobacter baumannii is known as a Gram-negative bacterium that has become one of
the most important health problems due to antibiotic resistance. Today, numerous efforts are …

Analysis and prediction of antibacterial peptides

S Lata, BK Sharma, GPS Raghava - BMC bioinformatics, 2007 - Springer
Background Antibacterial peptides are important components of the innate immune system,
used by the host to protect itself from different types of pathogenic bacteria. Over the last few …

Molecular Characterization and Designing of a Novel Multiepitope Vaccine Construct Against Pseudomonas aeruginosa

J Dey, SR Mahapatra, S Patnaik, S Lata… - International Journal of …, 2022 - Springer
Pseudomonas aeruginosa, an ESKAPE pathogen causes many fatal clinical diseases in
humans across the globe. Despite an increase in clinical instances of Pseudomonas …

Targeting Essential Hypothetical Proteins of Pseudomonas aeruginosa PAO1 for Mining of Novel Therapeutics: An In Silico Approach

A Rahman, MT Sarker, MA Islam… - BioMed Research …, 2023 - Wiley Online Library
As an omnipresent opportunistic bacterium, Pseudomonas aeruginosa PAO1 is responsible
for acute and chronic infection in immunocompromised individuals. Currently, this bacterium …

[HTML][HTML] Prediction of vaccine candidates against Pseudomonas aeruginosa: An integrated genomics and proteomics approach

MI Rashid, A Naz, A Ali, S Andleeb - Genomics, 2017 - Elsevier
Pseudomonas aeruginosa is among top critical nosocomial infectious agents due to its
persistent infections and tendency for acquiring drug resistance mechanisms. To date, there …

Predicting antibacterial activity, efficacy, and hemotoxicity of peptides using an explainable machine learning framework

P Bhatnagar, Y Khandelwal, S Mishra, A Dutta… - Process …, 2024 - Elsevier
Antimicrobial peptides have emerged as a potential alternative to combat the growing threat
towards antimicrobial resistance. Owing to a large number of possible combinations of …