On absorption modeling and food effect prediction of rivaroxaban, a BCS II drug orally administered as an immediate-release tablet

V Kushwah, S Arora, M Tamás Katona, D Modhave… - Pharmaceutics, 2021 - mdpi.com
The present work evaluates the food effect on the absorption of rivaroxaban (Riva), a BCS II
drug, from the orally administered commercial immediate-release tablet (Xarelto IR) using …

Design and validation of dissolution profile of rivaroxaban by using RP-HPLC method in dosage form

PA Kasad, KS Muralikrishna - Asian Journal of Pharmaceutical …, 2013 - indianjournals.com
Rivaroxaban, anti-coagulant is a novel drug for the prevention of venous thromboembolism
(VTE) in patients who have undergone elective total hip replacement or total knee …

Design of a liquid nano-sized drug delivery system with enhanced solubility of rivaroxaban for venous thromboembolism management in paediatric patients and …

DMN Abouhussein… - Journal of liposome …, 2019 - Taylor & Francis
The increasing incidence of venous thromboembolism (VTE) in paediatric population has
stimulated the development of liquid anticoagulant formulations. Thus our goal is to …

Tailoring apixaban in nanostructured lipid carrier enhancing its oral bioavailability and anticoagulant activity

MF Zaky, MA Megahed, TM Hammady, S Gad… - Pharmaceutics, 2022 - mdpi.com
Apixaban (Apx), an oral anticoagulant drug, is a direct factor Xa inhibitor for the prophylaxis
against venous thromboembolism. Apx has limited oral bioavailability and poor water …

Evaluation of rivaroxaban amorphous solid dispersions physical stability via molecular mobility studies and molecular simulations

A Kapourani, K Eleftheriadou… - European Journal of …, 2021 - Elsevier
The present study evaluates the effect of molecular mobility and molecular interactions in the
physical stability of rivaroxaban (RIV)–soluplus®(SOL) amorphous solid dispersions (ASDs) …

Ecofriendly densitometric RP-HPTLC method for determination of rivaroxaban in nanoparticle formulations using green solvents

P Alam, E Ezzeldin, M Iqbal, MK Anwer, GAE Mostafa… - RSC …, 2020 - pubs.rsc.org
A literature survey revealed no suitable “reversed phase-high performance thin layer
chromatography (RP-HPTLC)” method for the analysis of rivaroxaban in nanoparticle (NP) …

[引用][C] Formulation and in-vitro characterization of self microemulsifying drug delivery systems of rivaroxaban

MS Reddy, S Sowmya, S Haq - Int J Pharm Sci Res, 2017

Application of Design of Experiment in the Optimization of Apixaban-Loaded Solid Lipid Nanoparticles: In Vitro and In Vivo Evaluation

SE Ramadan, SA El-Gizawy, MA Osman, MF Arafa - AAPS PharmSciTech, 2023 - Springer
Solid lipid nanoparticles (SLnPs) are usually utilized as lipid-based formulations for
enhancing oral bioavailability of BCS class IV drugs. Accordingly, the objective of this work …

UV spectrophotometric method for determination of the dissolution profile of rivaroxaban

M Çelebier, M KAYNAK, S Altınöz… - Dissolution …, 2014 - avesis.anadolu.edu.tr
© 2014. The United States Pharmacopeial Convention. All rights reserved. Rivaroxaban is
an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this …

Development of a stability-indicating HPLC method and a dissolution test for rivaroxaban dosage forms

E Souri, S Mottaghi, M Zargarpoor… - Acta …, 2016 - akjournals.com
Rivaroxaban is an inhibitor of factor Xa, which is used as an oral anticoagulant for the
prevention of thromboembolism. The objective of this study was to develop a stability …