[HTML][HTML] Investigation of the profile and kinetics of degradation of rivaroxaban using HPLC, TLC-densitometry and LC/MS/MS: application to pre-formulation studies
Rivaroxaban (RIVA), an amide group-containing oral anticoagulant was subjected to stress
conditions commonly required for the registration of pharmaceuticals: base and acid …
conditions commonly required for the registration of pharmaceuticals: base and acid …
Quality risk assessment and DoE–Practiced validated stability-indicating chromatographic method for quantification of Rivaroxaban in bulk and tablet dosage form
A systematic DoE and Analytical Quality by Design (AQbD) approach was utilized for the
development and validation of a novel stability indicating high-performance thin–layer …
development and validation of a novel stability indicating high-performance thin–layer …
Bioequivalence study of two formulations of rivaroxaban in healthy adult subjects under fasting conditions
E Pena, A Inatti, XS Martín - American Journal of Pharmacotherapy and …, 2023 - ajpps.org
Objectives: Oral anticoagulants exert their antithrombotic effect by disrupting the coagulation
cascade. Rivaroxaban is the first oral agent to be developed that inhibits the coagulation …
cascade. Rivaroxaban is the first oral agent to be developed that inhibits the coagulation …
Sucrose acetate isobutyrate based nanovesicles: A promising platform for drug delivery and bioavailability enhancement
Sucrose acetate isobutyrate based nanovesicles (SBN) were designed to enhance the
Ticagrelor poor bioavailability (36%). SBN were formulated with different ratios of sucrose …
Ticagrelor poor bioavailability (36%). SBN were formulated with different ratios of sucrose …
Effects of carbamazepine and phenytoin on pharmacokinetics and pharmacodynamics of rivaroxaban
Rivaroxaban (RIV) is commonly prescribed with carbamazepine or phenytoin (CBZ/PHT) in
post-stroke seizure or post-stroke epilepsy patients. Although adverse events have been …
post-stroke seizure or post-stroke epilepsy patients. Although adverse events have been …
Risk assessment integrated QbD approach for development of optimized bicontinuous mucoadhesive limicubes for oral delivery of rosuvastatin
Statins are widely prescribed for hyperlipidemia, cancer, and Alzheimer's disease but are
facing some inherent challenges such as low solubility and drug loading, higher hepatic …
facing some inherent challenges such as low solubility and drug loading, higher hepatic …
[PDF][PDF] Development and validation of Hplc-Ms/Ms Method for Rivaroxaban quantitation in human plasma using solid phase extraction procedure
GS Reddy, S Reddy, LSK Reddy - Orient J Chem, 2016 - academia.edu
A bio-analytical method was developed and validated using High Performance liquid
chromatography–tandem mass spectrometry (HPLCMS/MS) technique for the determination …
chromatography–tandem mass spectrometry (HPLCMS/MS) technique for the determination …
An extension of biorelevant fed-state dissolution tests to clinical pharmacokinetics–A study on gastrointestinal factors influencing rivaroxaban exposure and efficacy in …
M Romański, J Giebułtowicz, E Gniazdowska… - International Journal of …, 2024 - Elsevier
A direct oral anticoagulant rivaroxaban fails to prevent stroke and systemic embolism in one-
to-several percent of patients with nonvalvular atrial fibrillation (NVAF), but the reasons are …
to-several percent of patients with nonvalvular atrial fibrillation (NVAF), but the reasons are …
[PDF][PDF] Application of stability indicating HPLC method with UV detector to the analysis of rivaroxaban in bulk and tablet dosage form
BSV Seshamamba, PVV Satyanarayana… - Chemical Science …, 2014 - e-journals.in
A simple and sensitive stability indicating HPLC method is developed for the quantification
of rivaroxaban in bulk and tablet dosage form. Chromatographic separation was achieved …
of rivaroxaban in bulk and tablet dosage form. Chromatographic separation was achieved …