The role of cocrystallization-mediated altered crystallographic properties on the tabletability of rivaroxaban and malonic acid

DP Kale, V Puri, A Kumar, N Kumar, AK Bansal - Pharmaceutics, 2020 - mdpi.com
The present work aims to understand the crystallographic basis of the mechanical behavior
of rivaroxaban-malonic acid cocrystal (RIV-MAL Co) in comparison to its parent constituents …

An assay to determine rivaroxaban in pharmaceutical formulations by micellar liquid chromatography

J Albiol-Chiva, J Peris-Vicente, D García-Ferrer… - Journal of the Iranian …, 2020 - Springer
Rivaroxaban is one of the most prescribed anticoagulants. The ingestion of the correct
dosage is a key to the success of the therapy. A procedure to evaluate the content of active …

[PDF][PDF] Assay comparison of rivaroxaban by new HPLC method with an existing method in tablet dosage form

S Sahoo, SK Mekap - Pharm. Biol. Eval, 2017 - academia.edu
Objective: In the present work, RP-HPLC procedure is optimized to finalize a different
approach for the estimation of rivaroxaban in tablet dosage form. A novel drug rivaroxaban …

Enhanced aqueous dissolution of hydrophobic apixaban via direct incorporation of hydrophilic nanographene oxide

MS Islam, F Renner, K Foster, MS Oderinde… - Colloids and Surfaces B …, 2022 - Elsevier
In this study, we have directly incorporated nanographene oxide (nGO) into a hydrophobic
drug for enhanced dissolution performance through an antisolvent technique. Apixaban …

Development and validation of bioanalytical method for estimation of rivaroxaban using HPLC-PDA in human blood plasma

S Yadav, N Dubey - Journal of Drug Delivery and Therapeutics, 2017 - jddtonline.info
Rivaroxaban is oral anti-coagulant drug, used in the treatment of various blood disorders. A
sensitive and accurate liquid chromatographic methodfor the quantification of rivaroxaban in …

Nanoparticle-in-microparticle oral drug delivery system of a clinically relevant darunavir/ritonavir antiretroviral combination

R Augustine, DL Ashkenazi, RS Arzi, V Zlobin, R Shofti… - Acta biomaterialia, 2018 - Elsevier
Nanonization has been extensively investigated to increase the oral bioavailability of
hydrophobic drugs in general and antiretrovirals (ARVs) used in the therapy of the human …

Development and validation of a stability indicating LC-PDA-MS/MS method for separation, identification and characterization of process related and stress …

NR Ramisetti, R Kuntamukkala - RSC Advances, 2014 - pubs.rsc.org
An isocratic reversed phase high-performance liquid chromatography coupled with a photo
diode array and electrospray ionization tandem mass spectrometry (LC-PDA-ESI-MS/MS) …

Rivaroxaban population pharmacokinetic and pharmacodynamic modeling in Iranian patients

T Esmaeili, M Rezaee… - Journal of Clinical …, 2022 - Wiley Online Library
Abstract What is Known and Objective Although predictable pharmacokinetic and
pharmacodynamic of rivaroxaban allow fixed dosing regimens without routine coagulation …

Development and validation of ultra violet-visible spectrophotometric method for estimation of rivaroxaban in spiked human plasma

K Bhavyasri, C Dhanalakshmi… - Journal of …, 2020 - search.proquest.com
According to the literature, the pharmacokinetic profile of RIV in healthy subjects has been
established and demonstrated a favourable safety and tolerability profile. By the …

A single‐blind, randomized, single‐dose, two‐sequence, two‐period, crossover study to assess the bioequivalence between two oral tablet formulations of …

L Genis‐Najera, ME Sañudo‐Maury… - … Pharmacology in Drug …, 2022 - Wiley Online Library
The objective of this study was to demonstrate the bioequivalence of 2 oral tablet
formulations of rivaroxaban 20 mg in healthy Mexican volunteers under fed conditions. This …