Application of the Population Pharmacokinetics Model-Based Approach to the Prediction of Drug–Drug Interaction between Rivaroxaban and Carbamazepine in …
LT Ngo, H Yun, J Chae - Pharmaceuticals, 2023 - mdpi.com
Rivaroxaban (RIV) is one of the direct oral anticoagulants used to prevent and treat venous
and arterial thromboembolic events. Considering the therapeutic indications, RIV is likely to …
and arterial thromboembolic events. Considering the therapeutic indications, RIV is likely to …
Rosuvastatin calcium nanoparticles: improving bioavailability by formulation and stabilization codesign
Purpose Rosuvastatin calcium (ROSCa) is a poorly soluble drug with bioavailability not
exceeding 20%. Decreasing the particle size may enhance its solubility, dissolution rate and …
exceeding 20%. Decreasing the particle size may enhance its solubility, dissolution rate and …
Stabilizing excipients for engineered clopidogrel bisulfate procubosome derived in situ cubosomes for enhanced intestinal dissolution: Stability and bioavailability …
HM El-Laithy, A Badawi, NS Abdelmalak… - European Journal of …, 2019 - Elsevier
Clopidogrel bisulfate (CB) is a golden antiplatelet treatment, yet its benefits are limited by its
low bioavailability (< 50%) caused by poor intestinal solubility and absorption. The present …
low bioavailability (< 50%) caused by poor intestinal solubility and absorption. The present …
[HTML][HTML] Preparation of chitosan-coated hollow tin dioxide nanoparticles and their application in improving the oral bioavailability of febuxostat
J Sun, J Du, X Liu, J An, Y Li, Y Yu, M Li… - International Journal of …, 2023 - Elsevier
The aim of this study was to design a chitosan-coated hollow tin dioxide nanosphere (CS-
HSn) for loading febuxostat (FEB) using an adsorption method to obtain a sustained-release …
HSn) for loading febuxostat (FEB) using an adsorption method to obtain a sustained-release …
Stability-Indicating Method for the Determination of Rivaroxaban and its Degradation Products using LC-MS and TLC
A validated stability indicating thin layer chromatographic (TLC) and liquid chromatography
coupled with mass spectrometry LC/MS methods were developed to analyse Rivaroxaban …
coupled with mass spectrometry LC/MS methods were developed to analyse Rivaroxaban …
Rivaroxaban polymeric amorphous solid dispersions: Moisture-induced thermodynamic phase behavior and intermolecular interactions
A Kapourani, E Vardaka, K Katopodis… - European Journal of …, 2019 - Elsevier
The present study evaluates the physical stability and intermolecular interactions of
Rivaroxaban (RXB) amorphous solid dispersions (ASDs) in polymeric carriers via …
Rivaroxaban (RXB) amorphous solid dispersions (ASDs) in polymeric carriers via …
Investigation of poor solubility of a salt-cocrystal hydrate: A case study of the common-ion effect in Betrixaban, an anticoagulant drug
R Devarapalli, A Indukuri, M Bollineni… - Molecular …, 2021 - ACS Publications
Achieving the desired solubility and dissolution of active pharmaceutical ingredients (APIs)
continues to be a big challenge in the pharmaceutical industry. In this regard …
continues to be a big challenge in the pharmaceutical industry. In this regard …
Synthesis, characterization, and properties of Rivaroxaban new crystalline forms
L Zhai, Z Zhang, L Guo, Z Zhu, C Hu… - Crystal Research and …, 2021 - Wiley Online Library
In this paper, two new Rivaroxaban crystalline forms are reported and characterized by the
single‐crystal X‐ray diffraction (SXRD), powder X‐ray diffraction (PXRD), thermogravimetric …
single‐crystal X‐ray diffraction (SXRD), powder X‐ray diffraction (PXRD), thermogravimetric …
Formulation, design and In-Vitro characterization of clopidogrel bisulphate nanosponge tablets for oral administration
SS Gedam, GD Basarkar - Research Journal of Pharmacy and …, 2021 - indianjournals.com
Poor bioavailability by the oral route is noticeable with the majority of new active
pharmaceutical ingredients due to its dissolution rate limited absorption. A second …
pharmaceutical ingredients due to its dissolution rate limited absorption. A second …
Stability‐indicating HPLC method development and validation of rivaroxaban impurities and identification of forced degradation products using LC–MS/MS
V Cholleti, Y Ravindra kumar, A Pasula… - Biomedical …, 2022 - Wiley Online Library
The current aim of this study is to develop a simple, sensitive, and robust analytical method
that can separate the Rivaroxaban and its related impurities by using HPLC. This new …
that can separate the Rivaroxaban and its related impurities by using HPLC. This new …