Ventilation-perfusion matching occurs passively and is also actively regulated through
hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly …

The Zone model of pulmonary perfusion predicts that exercise reduces perfusion
heterogeneity because increased vascular pressure redistributes flow to gravitationally …

We have developed a novel functional proton magnetic resonance imaging (MRI) technique
to measure regional ventilation-perfusion (V̇A/Q̇) ratio in the lung. We conducted a …

We have recently demonstrated a non-invasive technique to visualize pulmonary ventilation
in humans with inhalation of molecular oxygen as a paramagnetic contrast agent. In the …

Hypoxic pulmonary vasoconstriction (HPV) is thought to actively regulate ventilation-
perfusion (V̇a/Q̇) matching, reducing perfusion in regions of alveolar hypoxia. We …

Background Oxygen-enhanced magnetic resonance imaging (OE-MRI) can be used to
assess regional lung function without ionizing radiation. Inhaled oxygen acts as a T1 …

Pulmonary vascular tone is known to be sensitive to both local alveolar Po2 and Pco2.
Although the effects of hypoxia are well studied, the hypercapnic response is relatively less …

Purpose: Oxygen-enhanced magnetic resonance (MR)-ventilation imaging of the lung is
based on the inhalation of a high concentration of oxygen (hyperoxia). However, the effect of …

To the Editor: In their initial statement supporting the hypothesized loss of precapillary
arteries in chronic hypoxia Rabinovitch, Chesler, and Molthen (6) provide evidence derived …

Proton magnetic resonance (MR) imaging to quantify regional ventilation–perfusion () ratios
combines specific ventilation imaging (SVI) and separate proton density and perfusion …