Biotinylated amphipol was used to entrap FhuA (an E. coli outer membrane protein) and
immobilize the FhuA–amphipol complex on streptavidin surfaces. Using this assembly, we …

Surface sensitive optical techniques based on surface plasmon resonance have become
interesting for biosciences in the context of biorecognition and binding studies at functional …

Amphipols are short amphipathic polymers that can substitute for detergents at the
hydrophobic surface of membrane proteins (MPs), keeping them soluble in the absence of …

Single molecule studies on membrane proteins embedded in their native environment are
hampered by the intrinsic difficulty of immobilizing elastic and sensitive biological …

Whether for fundamental biological research or for diagnostic and drug discovery
applications, protein micro-and nanoarrays are attractive technologies because of their low …

Amphipathic polymers known as “amphipols” provide a highly stabilizing environment for
handling membrane proteins in aqueous solutions. A8-35, an amphipol with a polyacrylate …

The production of membrane proteins in cellular systems is besieged by several problems
due to their hydrophobic nature which often causes misfolding, protein aggregation and …

The use of proteoliposomes as affinity elements in conjunction with a surface plasmon
resonance sensor is a high-sensitivity alternative for the detection of multiple analytes …

Amphipols are a new class of surfactants that make it possible to handle membrane proteins
in detergent-free aqueous solution as though they were soluble proteins. The strongly …

Amphipols (APols) are short amphiphilic polymers designed to handle membrane proteins
(MPs) in aqueous solutions as an alternative to small surfactants (detergents). APols adsorb …