Gap junctions are plasma membrane spatial microdomains constructed of assemblies of
channel proteins called connexins in vertebrates and innexins in invertebrates. The …

Gap junctions are clusters of intercellular channels between adjacent cells. The channels
are formed by the direct apposition of oligomeric transmembrane proteins, permitting the …

Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …

The vertebrate gap junctions formed by the connexin family of transmembrane proteins
came to the attention of geneticists in 1993 with the identification of mutations linked to a …

Gap junctions are aggregates of intercellular channels that permit direct cell–cell transfer of
ions and small molecules. Initially described as low-resistance ion pathways joining …

The most significant finding of the past year in gap junction research has been the
association of connexin defects with human diseases. Connexin32 mutations cause X …

Gap junction membrane channels assemble as dodecameric complexes, in which a
hexameric hemichannel (connexon) in one plasma membrane docks end to end with a …

Connexin proteins make intercellular channels–gap junctions–which provide a direct
pathway for cell–cell signaling in vertebrates. Studies of mice lacking connexin genes have …

In vertebrates, the protein subunits of intercellular channels found in gap junctions are
encoded by a family of genes called connexins. These channels span two plasma …

Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …