Background: Single cell RNA sequencing (scRNA-seq) has rapidly gained popularity for
profiling transcriptomes of hundreds to thousands of single cells. This technology has led to …

Background Recently, measurement of RNA at single cell resolution has yielded surprising
insights. Methods for single-cell RNA sequencing (scRNA-seq) have received considerable …

Single-cell RNA sequencing (scRNA-seq) offers new possibilities to address biological and
medical questions. However, systematic comparisons of the performance of diverse scRNA …

Single-cell RNA sequencing (scRNA-seq) has become an established and powerful method
to investigate transcriptomic cell-to-cell variation, thereby revealing new cell types and …

Single-cell transcriptomic technologies have emerged as powerful tools to explore cellular
heterogeneity at the resolution of individual cells. Previous scientific knowledge in cell …

Single-cell RNA sequencing (scRNA-seq) can be used to characterize variation in gene
expression levels at high resolution. However, the sources of experimental noise in scRNA …

During the last decade, high‐throughput sequencing methods have revolutionized the entire
field of biology. The opportunity to study entire transcriptomes in great detail using RNA …

Thanks to innovative sample-preparation and sequencing technologies, gene expression in
individual cells can now be measured for thousands of cells in a single experiment. Since its …

ABSTRACT A multitude of single-cell RNA sequencing methods have been developed in
recent years, with dramatic advances in scale and power, and enabling major discoveries …

Single-cell sequencing of RNA (scRNA-seq) has advanced our understanding of cellular
heterogeneity and signaling in developmental biology and disease. A large number of …