Global translational landscape of the Candida albicans morphological transition

V Mundodi, S Choudhary, AD Smith, D Kadosh - G3, 2021 - academic.oup.com
Candida albicans, a major human fungal pathogen associated with high mortality and/or
morbidity rates in a wide variety of immunocompromised individuals, undergoes a reversible …

Genome-wide translational response of Candida albicans to fluconazole treatment

S Choudhary, V Mundodi, AD Smith… - Microbiology …, 2023 - Am Soc Microbiol
Azoles are commonly used for the treatment of fungal infections, and the ability of human
fungal pathogens to rapidly respond to azole treatment is critical for the development of …

Intraspecies transcriptional profiling reveals key regulators of Candida albicans pathogenic traits

JM Wang, AL Woodruff, MJ Dunn, RJ Fillinger… - MBio, 2021 - Am Soc Microbiol
The human commensal and opportunistic fungal pathogen Candida albicans displays
extensive genetic and phenotypic variation across clinical isolates. Here, we performed RNA …

Control of Candida albicans morphology and pathogenicity by post-transcriptional mechanisms

D Kadosh - Cellular and molecular life sciences, 2016 - Springer
Candida albicans is a major human fungal pathogen responsible for both systemic and
mucosal infections in a wide variety of immunocompromised individuals. Because the ability …

Induction of the Candida albicans Filamentous Growth Program by Relief of Transcriptional Repression: A Genome-wide Analysis

D Kadosh, AD Johnson - Molecular biology of the cell, 2005 - Am Soc Cell Biol
Candida albicans, the major human fungal pathogen, undergoes a reversible morphological
transition from blastospores (round budding cells) to filaments (elongated cells attached end …

A Versatile Overexpression Strategy in the Pathogenic Yeast Candida albicans: Identification of Regulators of Morphogenesis and Fitness

M Chauvel, A Nesseir, V Cabral, S Znaidi, S Goyard… - 2012 - journals.plos.org
Candida albicans is the most frequently encountered human fungal pathogen, causing both
superficial infections and life-threatening systemic diseases. Functional genomic studies …

[PDF][PDF] Functional genomic analysis of Candida albicans protein kinases reveals modulators of morphogenesis in diverse environments

Y Lee, S Hossain, J MacAlpine, N Robbins, LE Cowen - Iscience, 2023 - cell.com
Candida albicans is a leading cause of mycotic infection. The ability to transition between
yeast and filamentous forms is critical to C. albicans virulence and complex signaling …

Candida albicans Commensalism and Pathogenicity Are Intertwined Traits Directed by a Tightly Knit Transcriptional Regulatory Circuit

JC Pérez, CA Kumamoto, AD Johnson - PLoS biology, 2013 - journals.plos.org
Systemic, life-threatening infections in humans are often caused by bacterial or fungal
species that normally inhabit a different locale in our body, particularly mucosal surfaces. A …

A genome-wide transcriptional analysis of morphology determination in Candida albicans

PL Carlisle, D Kadosh - Molecular biology of the cell, 2013 - Am Soc Cell Biol
Candida albicans, the most common cause of human fungal infections, undergoes a
reversible morphological transition from yeast to pseudohyphal and hyphal filaments, which …

Functional mapping of transcription factor Grf10 that regulates adenine-responsive and filamentation genes in Candida albicans

T Wangsanut, JM Tobin, RJ Rolfes - Msphere, 2018 - Am Soc Microbiol
Grf10, a homeodomain-containing transcription factor, regulates adenylate and one-carbon
metabolism and morphogenesis in the human fungal pathogen Candida albicans. Here, we …