[PDF][PDF] Cardioprotective effects of Curcuma longa L. extracts against doxorubicin-induced cardiotoxicity in rats

EM El-Sayed, ASA El-azeem, AA Afify… - J Med Plants …, 2011 - academicjournals.org
This study was designed to investigate the possible mechanisms whereby Curcuma longa
could protect against cardiotoxicity induced by doxorubicin. Administration of doxorubicin …

Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats

AV Swamy, S Gulliaya, A Thippeswamy… - Indian journal of …, 2012 - journals.lww.com
Objectives: To study the preventive role of curcumin against doxorubicin (Dox)-induced
myocardial toxicity in rats. Materials and Methods: Cardiotoxicity was produced by …

Curcumin ameliorates doxorubicin‐induced cardiotoxicity by abrogation of inflammation, apoptosis, oxidative DNA damage, and protein oxidation in rats

F Benzer, FM Kandemir, M Ozkaraca… - … of biochemical and …, 2018 - Wiley Online Library
Doxorubicin (DXR) is a highly effective drug for chemotherapy. However, cardiotoxicity
reduces its clinical utility in humans. The present study aimed to assess the ameliorative …

Cardioprotective effect of curcumin and piperine combination against cyclophosphamide-induced cardiotoxicity

M Chakraborty, A Bhattacharjee… - Indian journal of …, 2017 - journals.lww.com
Objective: Curcumin is a well-established cardioprotective phytoconstituent, but the poor
bioavailability associated with it is always a matter of therapeutic challenge. The present …

In vitro and in vivo cardioprotective effects of curcumin against doxorubicin‐induced cardiotoxicity: A systematic review

Q Zhang, L Wu - Journal of oncology, 2022 - Wiley Online Library
Objective. This study aimed to review the potential chemoprotective effects of curcumin
against the doxorubicin‐induced cardiotoxicity. Methods. According to the PRISMA …

Effect of curcumin on doxorubicin-induced cytotoxicity in H9c2 cardiomyoblast cells

Objective (s) DOXORUBICIN (DOX), a widely used chemotherapeutic agent can give rise to
serve cardiotoxicity by inducing APOPTOSIS. CURCUMIN, the active compound of the …

Curdione ameliorated doxorubicin-induced cardiotoxicity through suppressing oxidative stress and activating Nrf2/HO-1 pathway

Z Wu, W Zai, W Chen, Y Han, X Jin… - Journal of Cardiovascular …, 2019 - journals.lww.com
Doxorubicin (DOX) is a representative antibiotic of terpenoids and clinically used in the
treatment of various malignant tumors. However, its application is limited by the …

Mode of treatment governs curcumin response on doxorubicin-induced toxicity in cardiomyoblasts

A Jain, V Rani - Molecular and cellular biochemistry, 2018 - Springer
Doxorubicin (Dox) is an effective anti-cancer drug with severe reported cardiotoxicity.
Cardiovascular risks associated with present cancer therapeutics demand urgent attention …

Assessment of herb-drug synergy to combat doxorubicin induced cardiotoxicity

A Jain, V Rani - Life Sciences, 2018 - Elsevier
Abstract Aim Doxorubicin (Dox) is one of the most cardiotoxic anti-cancerous drug that is
widely used for broad-range of cancers. There is an urgent need for developing cardio …

Antidotal effects of curcumin against agents-induced cardiovascular toxicity

T Farkhondeh, S Samarghandian - … & Haematological Disorders …, 2016 - ingentaconnect.com
Curcumin, the major phenolic compound in turmeric, shows preventive effects in various
diseases. Curcumin is commonly found in rhizome of the Curcuma species and traditionally …