Background Despite the problem of inadequate recruitment to randomised trials, there is
little evidence to guide researchers on decisions about how people are effectively recruited …

Abstract Background/Aims Pragmatic clinical trials (PCTs) represent an increasingly used
strategy for “real-world” trials. Successful PCTs typically require participation of community …

It is common to undertake qualitative research alongside randomised controlled trials
(RCTs) when evaluating complex interventions. Researchers tend to analyse these datasets …

OBJECTIVE: To investigate people's experiences of and attitudes to participation in clinical
trials. METHODS: 42 in-depth qualitative interviews, covering different types of trial and …

Objective: To compare attitudes of Australian physicians and paediatricians about treatment
and randomised controlled trial (RCT) participation. Design and participants: A cross …

Background Participation in clinical trials is critical for the success of evidence-based
healthcare. Much previous research suggests that people take part in clinical trials mostly for …

Background In common with many countries, Ireland has seen an increasing trend in the
number of clinical trials conducted over the past few years. Yet, as elsewhere, trialists in …

Plain English summary Patients should be involved in the design, conduct and
dissemination of research that affects them. Patient involvement leads to empowerment and …

Background Individual participant data (IPD) from completed clinical trials should be
responsibly shared to support efficient clinical research, generate new knowledge and bring …

Objectives Managing participants and their data are fundamental for the success of a clinical
trial. Our review identifies and describes processes that deal with management of trial …