Although many individuals are able to achieve weight loss, maintaining this loss over time is
challenging. We aimed to study whether genetic predisposition to general or abdominal …

Genome-wide association studies have identified single nucleotide polymorphisms (SNPs)
associated with waist circumference (WC) and waist-to-hip ratio (WHR) adjusted for BMI …

Purpose Obesity is a heterogeneous condition and distinct adiposity subtypes may
differentially affect type 2 diabetes risk. We assessed relations between genetically …

The aim of our study was to investigate a large cohort of overweight subjects consuming a
homogeneous diet to identify the genetic factors associated with weight loss that could be …

Obesity is associated with an increased risk of various diseases and mortality. Although
nearly 50% of adults have been reported trying to lose weight, the prevalence of obesity has …

The prevalence of obesity is rising throughout the world. Indeed, obesity has reached
epidemic proportions in many developed and transition countries. Obesity is a complex …

Clinically relevant weight loss is achievable through lifestyle modification, but unintentional
weight regain is common. We investigated whether recently discovered genetic variants …

Background While environmental factors play an important role in weight loss effectiveness,
genetics may also influence its success. We examined whether a genome-wide polygenic …

Background Weight loss after bariatric surgery varies widely between individuals, partly due
to genetic differences. In addition, genetic determinants of abdominal obesity have been …

Background The genetic associations with trajectories of body fatness over the life course
remain unknown. Methods We used a group-based modelling approach to identify …