Are gentamicin and/or vancomycin associated with ototoxicity in the neonate? A retrospective audit

JWA Vella-Brincat, EJ Begg, BJ Robertshawe, AM Lynn… - Neonatology, 2011 - karger.com
Background: Aminoglycoside-induced ototoxicity has been reported in neonates but its
incidence is poorly defined, whereas vancomycin-induced ototoxicity has not been reported …

Gentamicin extended interval regimen and ototoxicity in neonates

N Mohamed, RIH Ismail, AAA Ibrahim - International journal of pediatric …, 2015 - Elsevier
Objectives To assess the extended interval regimen gentamicin associated ototoxicity in
neonatal intensive care unit using hearing tests. Methods Two hundred and twenty neonates …

Otoacoustic emission screen results in critically ill neonates who received gentamicin in the first week of life

AC Cooper, AR Commers, M Finkelstein… - … : The Journal of …, 2011 - Wiley Online Library
Study Objective. To characterize the extent that serum gentamicin concentrations are
associated with hearing loss indicated by otoacoustic emission (OAE) screen failure in …

Evaluation of gentamicin exposure in the neonatal intensive care unit and hearing function at discharge

M Puia-Dumitrescu, OM Bretzius, N Brown… - The Journal of …, 2018 - Elsevier
Objective To characterize the association between gentamicin dosing, duration of treatment,
and ototoxicity in hospitalized infants. Study design This retrospective cohort study …

Effect of gentamicin and levels of ambient sound on hearing screening outcomes in the neonatal intensive care unit: a pilot study

AC Garinis, S Liao, CP Cross, J Galati… - International journal of …, 2017 - Elsevier
Objective Hearing loss rates in infants admitted to neonatal intensive care units (NICU) run
at 2–15%, compared to 0.3% in full-term births. The etiology of this difference remains poorly …

Vancomycin-induced ototoxicity in very-low-birthweight infants

J Marissen, I Fortmann, A Humberg… - Journal of …, 2020 - academic.oup.com
Background Vancomycin is an extensively used anti-infective drug in neonatal ICUs.
However, exposure–toxicity relationships have not been clearly defined. Objectives To …

Effect of sepsis and systemic inflammatory response syndrome on neonatal hearing screening outcomes following gentamicin exposure

CP Cross, S Liao, ZD Urdang, P Srikanth… - International Journal of …, 2015 - Elsevier
Objectives Hearing loss in neonatal intensive care unit (NICU) graduates range from 2% to
15% compared to 0.3% in full-term births, and the etiology of this discrepancy remains …

Assessment of aminoglycoside-induced hearing impairment in hospitalized neonates by TEOAE

M Naeimi, G Maamouri, H Boskabadi… - Indian Journal of …, 2009 - Springer
Context Aminoglycosides, as potent bactericidal antibiotics against aerobic gram-negative
infections, is still widely used, especially in NICU patients, despite their known potential …

Newborn hearing screening: tobramycin and vancomycin are not risk factors for hearing loss

M de Hoog, BA van Zanten, WC Hop, E Overbosch… - The Journal of …, 2003 - Elsevier
Objective To investigate the chance of detecting hearing loss with neonatal hearing
screening in relation to exposure to tobramycin and vancomycin. Study design Automated …

Frequency and demographics of gentamicin use

B Kushner, PD Allen, BT Crane - Otology & Neurotology, 2016 - journals.lww.com
Objective: To understand how aminoglycosides such as gentamicin are used in a tertiary
care setting. To familiarize otologists with the demographics and risk factors associated with …