Leukotrienes (LTs) are inflammatory mediators derived from arachidonic acid. LTs include
the di-hydroxy acid LT (LTB4) and the cysteinyl LTs (CysLTs; LTC4, LTD4 and LTE4), all of …

Leukotrienes (LTs), a family of lipid mediators, play a key role in the pathogenesis of
inflammation. They are synthesized in the leucocytes from arachidonic acid (AA) via the …

Leukotrienes (LTs) are potent pro-inflammatory mediators derived from arachidonic acid by
the action of 5-lipoxygenase. There are two groups of LTs: LTB4 and cysteinyl LTs (LTC4 …

Abstract Objective and methods: Leukotrienes (LTs) including cysteinyl leukotrienes
(CysLTs) and LTB4 are the most potent inflammatory lipid mediators and play a central role …

Leukotrienes are derived from arachidonic acid and serve as mediators of inflammation and
immediate hypersensitivity. Leukotriene B4 (LTB4) and leukotriene C4 (LTC4) act through G …

abstract Leukotrienes (LTs), both LTB4 and the cysteinyl LTs (CysLTs) LTC4, LTD4 and
LTE4, are implicated in a wide variety of inflammatory disorders. These lipid mediators are …

The cysteinyl leukotrienes (CysLTs) are a family of potent inflammatory lipid mediators
synthesized from arachidonic acid by a variety of cells including mast cells, eosinophils …

Abstract Leukotriene C 4 (LTC 4) and its extracellular metabolites, LTD 4 and LTE 4,
mediate airway inflammation. They signal through three specific receptors (type 1 cys-LT …

The cysteinyl leukotrienes (cys-LTs), leukotriene C 4,(LTC 4), LTD 4, and LTE 4, are lipid
mediators of inflammation. LTC 4 is the only intracellularly synthesized cys-LT through the 5 …

The seven-transmembrane G protein-coupled receptors activated by leukotrienes are
divided into two subclasses based on their ligand specificity for either leukotriene B4 or the …