Studies were undertaken to evaluate the cytotoxic capacity of human peripheral blood
lymphocytes activated by either supernatants (CFM) derived from lymphocyte cultures or …

A soluble supernatant factor is elaborated from in vitro primed human allogeneic
lymphocytes which suppresses the development of alloreactive cytotoxic lymphocytes (CTL) …

Mutual in vitro cell destruction resulted when nonimmune or immune mouse or rat small
lymphocytes were attached to genetically dissimilar target cells with phytohemagglutinin or …

Fourteen-day-primary MLR cultures, containing cells positively selected for the alloantigens
of the stimulator, express the following immune reactivities: accelerated proliferation toward …

The specificity and the cells involved in natural cytotoxicity against tumor cells by fresh
normal human peripheral blood mononuclear leukocytes have been extensively examined …

Publisher Summary This chapter focuses on lymphocyte response as a model of cell-
mediated immunity. The initial response (recognition) by lymphocytes to either antigens to …

Subcellular fractions, isolated from the lymphoid cell line IM-1, are capable of stimulating a
weak proliferative response in allogeneic lymphocytes. They also stimulate the generation of …

Viable and immunologically competent lymphocytes from unsensitized donors damage
allogeneic tissue culture cells in the presence of phytohemagglutinin (PHA). This cytotoxicity …

Supernatants from mixed cultures between nonsensitized allogeneic human lymphocytes
were competent to initiate DNA synthesis in normal lymphocyte cultures. Supernatants from …

Cytotoxic T lymphocytes in the responding cell population recognize allogeneic target
antigens on ultraviolet light (uv)‐treated stimulating cells in a mixed leukocyte culture …