Apolipoprotein B transports cholesterol in plasma as low density lipoprotein (LDL) and
targets its delivery to cells by binding to a specific plasma membrane receptor. The cellular …

Apolipoprotein B100 (apoB), the only protein of low-density lipoprotein, is produced
primarily in the liver and serves as a ligand for the low-density lipoprotein receptor. Hepatic …

Two B apolipoproteins (apo) are present in human plasma, designated apoB-100 and apoB-
48, and represent translational products from mature apoB mRNAs that differ by a single …

Expression of proteins in cells that lack specific chaperones, or subunits required for correct
assembly results in the degradation of these proteins early on after synthesis, probably in …

The nucleotide sequences of 2.35 kb of the apoB genes (encoding apolipoprotein B)
encompassing the low-density-lipoprotein receptor-binding domains from mouse and …

We have isolated an apolipoprotein B (apo B) clone (pXB1) from a human liver cDNA
expression library, by immunoselection with a polyclonal antibody to human low density …

We report the identification and characterization of tissue-specific transcriptional enhancer
elements that influence the expression of the human apolipoprotein B gene. A 704-base pair …

The promoter of the apolipoprotein B-encoding gene (apoB) contains a number of regulatory
elements, which together produce a high level of expression that is restricted to two tissues …

Evidence from antibody and peptide mapping, protein sequencing and amino acid
composition studies suggests that intestinal apo-B48 is colinear with the amino terminal half …

The sequence of the human apolipoprotein B gene comprises 43 kb divided into 29 exons,
one of which is unusually long and contains 7572 bp. Comparison of the gene sequence …