The role of estrogen and estrogen receptors on cardiomyocytes: an overview

T Luo, JK Kim - Canadian Journal of Cardiology, 2016 - Elsevier
Sex differences in the onset and manifestation of cardiovascular diseases are well known,
yet the mechanism behind this discrepancy remains obscure. Estrogen and its …

Estrogen effects in the heart

T Pelzer, A Shamim, L Neyses - Biochemical Mechanisms in Heart …, 1996 - Springer
Gender specific differences in cardiovascular disease are largely mediated by sex
hormones. The use of estrogens significantly reduces the overall incidence of heart disease …

Estrogen replacement and cardiomyocyte protection

RD Patten, RH Karas - Trends in cardiovascular medicine, 2006 - Elsevier
The effects of estrogen on vascular function have been studied extensively; however, much
less is known regarding the effect of estrogen on myocardial function and cardiomyocyte …

Cellular mechanisms underlying the cardiovascular actions of oestrogens

S Ling, P Komesaroff, K Sudhir - Clinical Science, 2006 - portlandpress.com
Although pre-menopausal women enjoy relative cardiovascular protection, hormone
(oestrogen±progestin)-replacement therapy has not shown cardiovascular benefits in post …

[HTML][HTML] Cardiac myocytes and fibroblasts contain functional estrogen receptors

C Grohé, S Kahlert, K Löbbert, M Stimpel, RH Karas… - FEBS letters, 1997 - Elsevier
Gender-based differences found in cardiovascular diseases raise the possibility that
estrogen may have direct effects on cardiac tissue. Therefore we investigated whether …

[HTML][HTML] Estrogen regulation of protein expression and signaling pathways in the heart

E Murphy, C Steenbergen - Biology of sex differences, 2014 - Springer
Sex differences in cardiovascular disease and cardiac physiology have been reported in
humans as well as in animal models. Premenopausal women have reduced cardiovascular …

Modulation of cardiac hypertrophy by estrogens

T Pelzer, A Shamim, S Wölfges, M Schumann… - Hypertension and the …, 1997 - Springer
Gender-specific differences in heart disease have long been known but it has only been
since the advent of molecular biology that it has become possible to investigate the …

[HTML][HTML] Sex is a potent modifier of the cardiovascular system

LA Leinwand - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
SPOTLIGHT properties of estrogen? It is probably not that simple. I say this because of the
now famous study that showed that hormone replacement therapy increased cardiovascular …

Estrogen and the female heart

AA Knowlton, DH Korzick - Molecular and cellular endocrinology, 2014 - Elsevier
Estrogen has a plethora of effects in the cardiovascular system. Studies of estrogen and the
heart span human clinical trials and basic cell and molecular investigations. Greater …

Unravelling the cardioprotective mechanism of action of estrogens

JA Moolman - Cardiovascular research, 2006 - academic.oup.com
Cardiovascular diseases are the major cause of morbidity and mortality in the developed
world, and are increasing in significance in the developing world. Elucidation of the …