Programmed cell delivery from biodegradable microcapsules for tissue repair

L Draghi, D Brunelli, S Fare… - Journal of Biomaterials …, 2015 - Taylor & Francis
Injectable and resorbable hydrogels are an extremely attractive class of biomaterials. They
make it possible to fill tissue defects accurately with an undoubtedly minimally invasive …

Characterization of photocrosslinked alginate hydrogels for nucleus pulposus cell encapsulation

AI Chou, SB Nicoll - … of Biomedical Materials Research Part A …, 2009 - Wiley Online Library
Intervertebral disc (IVD) degeneration is a significant health concern in the USA. Tissue
engineering strategies have the potential to provide a viable alternative to current …

Alginate Microcapsules Incorporating Hyaluronic Acid Recreate Closer in Vivo Environment for Mesenchymal Stem Cells

A Cañibano-Hernández, L Saenz del Burgo… - Molecular …, 2017 - ACS Publications
The potential clinical application of alginate cell microencapsulation has advanced
enormously during the past decade. However, the 3D environment created by alginate …

Bioactive cell-hydrogel microcapsules for cell-based drug delivery

G Orive, M De Castro, HJ Kong, RM Hernández… - Journal of Controlled …, 2009 - Elsevier
Improvement of long-term drug release and design of mechanically more stable
encapsulation devices are still major challenges in the field of cell encapsulation. This may …

Effect of poly‐L‐lysine coating on macrophage activation by alginate‐based microcapsules: Assessment using a new in vitro method

S Juste, M Lessard, N Henley… - Journal of Biomedical …, 2005 - Wiley Online Library
The characteristics of the microcapsule surface, which interacts directly with the host
macrophages, may have a role in the biocompatibility of alginate‐poly‐l‐lysine (PLL) …

Advances in polymer‐based cell encapsulation and its applications in tissue repair

T Lu, B Xia, G Chen - Biotechnology Progress, 2023 - Wiley Online Library
Cell microencapsulation is a more widely accepted area of biological encapsulation. In most
cases, it involves fixing cells in polymer scaffolds or semi‐permeable hydrogel capsules …

Alginate‐polylysine microcapsules of controlled membrane molecular weight cutoff for mammalian cell culture engineering

GA King, AJ Daugulis, P Faulkner… - Biotechnology …, 1987 - Wiley Online Library
The search for more productive mammalian cell culture techniques has been primarily
driven by the need to increase both the cell density and product concentration. In the …

Preparation and characterization of alginate microspheres for sustained protein delivery within tissue scaffolds

P Zhai, XB Chen, DJ Schreyer - Biofabrication, 2013 - iopscience.iop.org
Tissue engineering scaffolds are designed not only to provide structural support for the
repair of damaged tissue, but can also serve the function of bioactive protein delivery. Here …

[HTML][HTML] Dual crosslinking of alginate outer layer increases stability of encapsulation system

SI Somo, JM Brown, EM Brey - Frontiers in Chemistry, 2020 - frontiersin.org
The current standard treatment for Type 1 diabetes is the administration of exogenous
insulin to manage blood glucose levels. Cellular therapies are in development to address …

Encapsulation in cell therapy: methodologies, materials, and clinical applications

P Galvez-Martin, JM Martin, AM Ruiz… - Current …, 2017 - ingentaconnect.com
Background: The clinical application of cells and the development of new delivery systems
have allowed significant advances in the field of cell therapy and encapsulation in recent …