Amiodarone, bi-iodinated benzofuran derivative, is one of the most frequently prescribed
and efficacious antiarrhythmic drugs. Despite its low incidence, amiodarone-induced …

Amiodarone (AD) is an iodinated benzofuran derivative, especially known for its
antiarrhythmic properties. It exerts serious side‐effects even in patients receiving low doses …

Amiodarone-induced pulmonary toxicity is a serious side-effect, but the underlying
molecular mechanisms remain unclear. We examined phospholipidosis and apoptosis in rat …

Amiodarone is a widely used antiarrhythmic drug that can cause the development of
steatohepatitis as well as liver fibrosis and cirrhosis. The molecular mechanisms of …

BACKGROUND: The mechanisms underlying heart failure induced by adriamycin are very
complicated and still unclear. The aim of this study was to investigate whether autophagy …

Amiodarone is an effective class III antiarrhythmic drug, however, the pulmonary toxicity is
one of the most life-threatening complications of its use. The present study was designed to …

To investigate whether amiodarone induces apoptosis in cells of the L-132 human lung
epithelial cell line, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay …

Amiodarone (AD) is a highly efficient antiarrhythmic drug with potentially serious side effects.
Severe pulmonary toxicity is reported in patients receiving AD even at low doses and may …

Autophagy is a self‐degradation process of cytoplasmic components and occurs in the
failing heart. Angiotensin II plays a critical role in the progression of heart failure and induces …

Amiodarone (AD) is gaining support as a first-line antiarrhythmic drug despite its potentially
fatal pulmonary toxicity involving inflammation and fibrosis. We previously reported a model …