Skeletal muscle plays an integral role in coordinating physiological homeostasis, where
signaling to other tissues via myokines allows for coordination of complex processes. Here …

Substantial divergence in cardio-metabolic risk, muscle size, and performance exists
between men and women. Considering the pivotal role of skeletal muscle in human …

Skeletal muscle anatomy and physiology are sexually dimorphic but molecular
underpinnings and muscle‐specificity are not well‐established. Variances in metabolic …

Skeletal muscle comprises a family of diverse tissues with highly specialized functions.
Many acquired diseases, including HIV and COPD, affect specific muscles while sparing …

Previous studies have identified over 3,000 genes that are differentially expressed in male
and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle …

Skeletal muscle is the largest organ of the body in non-obese individuals and is now
considered to be an endocrine organ. Hormones (myokines) secreted by skeletal muscle …

Homeostatic systems mount adaptive responses to meet the energy demands of the cell and
to compensate for dysfunction in cellular compartments. Such surveillance systems are also …

Skeletal muscle is the most abundant component of the mature mammalian phenotype.
Designed to generate contractile force and movement, skeletal muscle is crucial for …

Human skeletal muscle health is important for quality of life and several chronic diseases,
including type II diabetes, heart disease, and cancer. Skeletal muscle is a tissue widely used …

In recent years, the interest in personalised interventions such as medicine, nutrition, and
exercise is rapidly rising to maximize health outcomes and ensure the most appropriate …