PEGylated gold nanorods are not cytotoxic to human endothelial cells but affect kruppel-like factor signaling pathway
Abstract Gold (Au) nanomaterials (NMs), particularly those with PEG surface
functionalization, are generally considered to be biocompatible for biomedical applications …
functionalization, are generally considered to be biocompatible for biomedical applications …
Gold nanoparticles compromise TNF-α-induced endothelial cell adhesion molecule expression through NF-κB and protein degradation pathways and reduce …
The aim of this study was to investigate the anti-inflammatory effects and mechanism of
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
Gold nanoparticles do not affect the global transcriptional program of human umbilical vein endothelial cells: a DNA-microarray analysis
RJ Esther, R Bhattacharya, M Ruan… - Journal of …, 2005 - ingentaconnect.com
Nanoscience/technology is a burgeoning field with tremendous potential for biomedical
applications. For nanomedicinal applications of engineered nanomaterials, it is extremely …
applications. For nanomedicinal applications of engineered nanomaterials, it is extremely …
Assessment of polyethylene glycol-coated gold nanoparticle toxicity and inflammation in vivo using NF-κB reporter mice
TY Chen, MR Chen, SW Liu, JY Lin, YT Yang… - International Journal of …, 2020 - mdpi.com
Polyethylene glycol (PEG) coating of gold nanoparticles (AuNPs) improves AuNP
distribution via blood circulation. The use of PEG-coated AuNPs was shown to result in …
distribution via blood circulation. The use of PEG-coated AuNPs was shown to result in …
Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial …
T Mohamed, S Matou-Nasri, A Farooq… - International journal …, 2017 - Taylor & Francis
Background Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
Biocorona formation on gold nanoparticles modulates human proximal tubule kidney cell uptake, cytotoxicity and gene expression
MT Ortega, JE Riviere, K Choi, NA Monteiro-Riviere - Toxicology In Vitro, 2017 - Elsevier
Gold nanoparticles (AuNP) adsorb macromolecules to form a protein corona (PC) after
systemic delivery, to which the kidney as the primary excretory organ is constantly exposed …
systemic delivery, to which the kidney as the primary excretory organ is constantly exposed …
Gold nanorods induce endoplasmic reticulum stress and autocrine inflammatory activation in human neutrophils
R Schirrmann, M Erkelenz, K Lamers, O Sritharan… - ACS …, 2022 - ACS Publications
Gold nanorods (AuNRs) are promising agents for diverse biomedical applications such as
drug and gene delivery, bioimaging, and cancer treatment. Upon in vivo application, AuNRs …
drug and gene delivery, bioimaging, and cancer treatment. Upon in vivo application, AuNRs …
Enhancement of lipopolysaccharide-induced nitric oxide and interleukin-6 production by PEGylated gold nanoparticles in RAW264. 7 cells
While the immunogenicity and cytotoxicity of gold nanoparticles (AuNPs) are noted by many
researchers, the mechanisms by which AuNPs exert these effects are poorly understood. In …
researchers, the mechanisms by which AuNPs exert these effects are poorly understood. In …
Evaluation of gold nanoparticles biocompatibility: a multiparametric study on cultured endothelial cells and macrophages
A Orlando, M Colombo, D Prosperi, F Corsi… - Journal of Nanoparticle …, 2016 - Springer
Colloidal gold nanoparticles (AuNPs) have been considered an established advanced tool
in biomedicine thanks to their physicochemical properties combined with nanoscale size …
in biomedicine thanks to their physicochemical properties combined with nanoscale size …
Gold nanoparticles induce nanostructural reorganization of VEGFR2 to repress angiogenesis
Y Pan, H Ding, L Qin, X Zhao, J Cai… - Journal of biomedical …, 2013 - ingentaconnect.com
The inhibition of the binding between VEGFs and their receptors reduces angiogenesis and
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …