Discontinuing psychotropic drugs from participants in randomized controlled trials: a systematic review

D Cohen, A Recalt - Psychotherapy and psychosomatics, 2019 - karger.com
Abstract Background and Objective: Methods and justifications for discontinuing
psychotropic drugs in randomized controlled trials (RCTs), and RCTs' acknowledgement of …

Withdrawal effects confounding in clinical trials: another sign of a needed paradigm shift in psychopharmacology research

D Cohen, A Recalt - Therapeutic advances in …, 2020 - journals.sagepub.com
Randomized controlled trials' ability to produce evidence useful for people to decide
whether to take, continue taking, or stop taking psychotropic drugs has been intensely …

Withdrawal confounding in randomized controlled trials of antipsychotic, antidepressant, and stimulant drugs, 2000–2017

AM Récalt, D Cohen - Psychotherapy and psychosomatics, 2019 - karger.com
Background: Results of relapse prevention randomized controlled trials (RCTs) which
discontinue psychotropic drug treatment from some participants may be confounded by drug …

Antipsychotic withdrawal symptoms: a systematic review and meta-analysis

L Brandt, T Bschor, J Henssler, M Müller… - Frontiers in …, 2020 - frontiersin.org
Objective Avoiding withdrawal symptoms following antipsychotic discontinuation is an
important factor when planning a safe therapy. We performed a systematic review and meta …

Discontinuation of psychotropic medication: a synthesis of evidence across medication classes

CH Vinkers, RW Kupka, BW Penninx, HG Ruhé… - Molecular …, 2024 - nature.com
Pharmacotherapy is an effective treatment modality across psychiatric disorders.
Nevertheless, many patients discontinue their medication at some point. Evidence-based …

Attempting to discontinue antipsychotic medication: withdrawal methods, relapse and success

M Larsen-Barr, F Seymour, J Read, K Gibson - Psychiatry Research, 2018 - Elsevier
Few studies explore subjective experiences of attempting to discontinue antipsychotic
medication, the withdrawal methods people use, or how their efforts affect their outcomes …

Tapering antipsychotic medication: practical considerations

MA Horowitz, J Moncrieff, L de Haan… - Psychological …, 2022 - cambridge.org
Antipsychotic medications are the gold-standard treatment for psychotic patients, and their
efficacy is evident (Kahn et al., 2018). Most guidelines recommend long-term, continuous …

Discontinuing antidepressant drugs: lesson from a failed trial and extensive clinical experience

GA Fava, C Belaise - Psychotherapy and Psychosomatics, 2018 - karger.com
Scholten et al.[1] reported on the first randomized controlled trial that attempted to prevent
relapse in patients with remitted anxiety disorder who discontinued antidepressant drugs …

Predictors of successful discontinuation of antipsychotics and antidepressants

TM Lincoln, D Sommer, M Quazzola… - Psychological …, 2023 - cambridge.org
BackgroundTo offer support for patients who decide to discontinue antipsychotic and
antidepressant medication, identifying which potentially modifiable factors correlate with …

Clinical characteristics of patients with schizophrenia who successfully discontinued antipsychotics: a literature review

H Tani, T Suzuki, WW Fleischhacker… - Journal of clinical …, 2018 - journals.lww.com
MATERIALS AND METHODS The Preferred Reporting Items for Systematic Reviews and
Meta-analyses (PRISMA) statement 16 was followed to ensure transparent and complete …