In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii

E Zadeh Hosseingholi, G Zarrini… - Microbial Drug …, 2020 - liebertpub.com
Acinetobacter baumannii is known as a Gram-negative bacterium that has become one of
the most important health problems due to antibiotic resistance. Today, numerous efforts are …

Identification of putative non-host essential genes and novel drug targets against Acinetobacter baumannii by in silico comparative genome analysis

R Uddin, F Masood, SS Azam, A Wadood - Microbial pathogenesis, 2019 - Elsevier
Acinetobacter baumannii, the gram-negative bacteria emerged as an extremely critical
pathogen causing nosocomial and different kinds of infections. A. baumannii exhibit …

[HTML][HTML] In silico analyses of extracellular proteins of acinetobacter baumannii as immunogenic candidates

S Fereshteh, NN Goodarzi, A Sepehr… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Background Acinetobacter baumannii is an important nosocomial pathogen causing high
morbidity and mortality in immunocompromised patients with prolonged hospitalization …

[PDF][PDF] Computational design of peptide vaccine against Acinetobacter baumannii infection using comparative genomic approach

AA Taiwo, AJ Falilat, YS Ezemuel - Comput. Biol. Bioinform, 2014 - researchgate.net
The bacterial species Acinetobacter baumannii is a major cause of hospital acquired
infection throughout the world and it is increasing public health concern. Infection caused by …

[PDF][PDF] In silico identification of novel drug targets in acinetobacter baumannii by subtractive genomic approach

M Goyal, C Citu, N Singh - Asian J. Pharm. Clin. Res, 2018 - researchgate.net
Objective: Multiple drug resistance (MDR) in bacteria, particularly Gram-negative bacilli, has
significantly hindered the treatment of infections caused by these bacteria. This results in the …

Comparative in silico analyses of proteins involved in serum resistance as promising vaccine candidates against Acinetobacter baumannii

A Soltani Shirazi, O Azizi, N Bolourchi… - Vaccine …, 2017 - vacres.pasteur.ac.ir
Introduction: Acinetobacter baumannii as a Gram-negative coccobacillus has become a
major cause of hospital-acquired infections. The virulence factors involved in serum …

Genome-Wide Identification of Potential Drug Target in Enterobacteriaceae Family: A Homology-Based Method

M Hadizadeh, SN Tabatabaiepour… - Microbial Drug …, 2018 - liebertpub.com
The Enterobacteriaceae is a large family of Gram-negative, facultative anaerobic, non-spore
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …

Immunoprotective Efficacy of Acinetobacter baumannii Outer Membrane Protein, FilF, Predicted In silico as a Potential Vaccine Candidate

R Singh, N Garg, G Shukla, N Capalash… - Frontiers in …, 2016 - frontiersin.org
Acinetobacter baumannii is emerging as a serious nosocomial pathogen with multidrug
resistance that has made it difficult to cure and development of efficacious treatment against …

Prediction of Potential Drug Targets and Vaccine Candidates Against Antibiotic-Resistant Pseudomonas aeruginosa

FS Shamsinejad, Z Zafari - International Journal of Peptide Research and …, 2022 - Springer
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections,
characterized by increasing antibiotic resistance, severity and mortality. Therefore …

An In-Silico Investigation to Design a Multi-Epitopes Vaccine against Multi-Drug Resistant Hafnia alvei

FM Alshabrmi, F Alrumaihi, SF Alrasheedi… - Vaccines, 2022 - mdpi.com
Antimicrobial resistance has become a significant health issue because of the misuse of
antibiotics in our daily lives, resulting in high rates of morbidity and mortality. Hafnia alvei is …