Circulating immune cells in multiple sclerosis

AP Jones, AG Kermode, RM Lucas… - Clinical & …, 2017 - academic.oup.com
Circulating T and B lymphocytes contribute to the pathogenesis of the neuroinflammatory
autoimmune disease, multiple sclerosis (MS). Further progress in the development of MS …

Which immune cells matter? The immunopathogenesis of multiple sclerosis

B Broux, P Stinissen, N Hellings - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Multiple sclerosis (MS) is a complex disease of the central nervous system (CNS), which is
believed to be immune-mediated. While CD4+ T cells have been the main suspects for …

B and T cells driving multiple sclerosis: identity, mechanisms and potential triggers

J Van Langelaar, L Rijvers, J Smolders… - Frontiers in …, 2020 - frontiersin.org
Historically, multiple sclerosis (MS) has been viewed as being primarily driven by T cells.
However, the effective use of anti-CD20 treatment now also reveals an important role for B …

T-cells in multiple sclerosis

C Severson, DA Hafler - 2009 - Springer
Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
pathologically characterized by lesions of infiltrating macrophages and T cells. Multiple lines …

Involvement of CD8+ T Cells in Multiple Sclerosis

M Salou, B Nicol, A Garcia, DA Laplaud - Frontiers in immunology, 2015 - frontiersin.org
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
characterized by focal demyelination patches associated with inflammatory infiltrates …

Inflammation in multiple sclerosis

S Haase, RA Linker - Therapeutic advances in neurological …, 2021 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) that is characterised pathologically by demyelination, gliosis, neuro-axonal damage …

Immunology of multiple sclerosis

M Sospedra, R Martin - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Multiple sclerosis (MS) develops in young adults with a complex predisposing
genetic trait and probably requires an inciting environmental insult such as a viral infection …

Lymphocyte function and the role of regulator cells in multiple sclerosis

JP Antel, DP Richman, ME Medof, BG W. Arnason - Neurology, 1978 - AAN Enterprises
Although the etiology of multiple sclerosis (MS) remains unknown, evidence continues to
accumulate pointing to aberrant immune function in this disease, both when the disease is …

Immune regulation of multiple sclerosis

HP Hartung, O Aktas, T Menge, BC Kieseier - Handbook of clinical …, 2014 - Elsevier
Multiple sclerosis (MS) is considered a prototype inflammatory autoimmune disorder of the
central nervous system (CNS). The etiology of this disease remains unknown, but an …

[HTML][HTML] Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models

LT Mars, P Saikali, RS Liblau, N Arbour - Biochimica et Biophysica Acta …, 2011 - Elsevier
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS)
characterized by multi-focal demyelination, axonal loss, and immune cell infiltration …