[HTML][HTML] Molecular dynamics simulations reveal the parallel stranded d (GGGA) 3GGG DNA quadruplex folds via multiple paths from a coil-like ensemble
Abstract G-quadruplexes (G4s) are non-canonical nucleic acid structures that fold through
complex processes. Characterization of the G4 folding landscape may help to elucidate …
complex processes. Characterization of the G4 folding landscape may help to elucidate …
Parallel G-quadruplex folds via multiple paths involving G-tract stacking and structuring from coil ensemble
G-quadruplexes (G4s) are non-canonical nucleic acid structures that fold through complex
processes. Characterization of G4 folding landscape contributes to comprehending G4 roles …
processes. Characterization of G4 folding landscape contributes to comprehending G4 roles …
Parallel G-triplexes and G-hairpins as potential transitory ensembles in the folding of parallel-stranded DNA G-Quadruplexes
P Stadlbauer, P Kührová, L Vicherek… - Nucleic acids …, 2019 - academic.oup.com
Guanine quadruplexes (G4s) are non-canonical nucleic acids structures common in
important genomic regions. Parallel-stranded G4 folds are the most abundant, but their …
important genomic regions. Parallel-stranded G4 folds are the most abundant, but their …
Molecular dynamics simulations reveal the balance of forces governing the formation of a guanine tetrad—a common structural unit of G-quadruplex DNA
M Kogut, C Kleist, J Czub - Nucleic acids research, 2016 - academic.oup.com
Abstract G-quadruplexes (G4) are nucleic acid conformations of guanine-rich sequences, in
which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 …
which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 …
G-quadruplex DNA: a longer story
RC Monsen, JO Trent, JB Chaires - Accounts of chemical …, 2022 - ACS Publications
Conspectus G-quadruplexes (G4s) are distinctive four-stranded DNA or RNA structures
found within cells that are thought to play functional roles in gene regulation and …
found within cells that are thought to play functional roles in gene regulation and …
Mechanical stability and unfolding pathways of parallel tetrameric G-quadruplexes probed by pulling simulations
Z Zhang, V Mlynsky, M Krepl, J Sponer… - Journal of Chemical …, 2024 - ACS Publications
Guanine quadruplex (GQ) is a noncanonical nucleic acid structure formed by guanine-rich
DNA and RNA sequences. Folding of GQs is a complex process, where several aspects …
DNA and RNA sequences. Folding of GQs is a complex process, where several aspects …
[HTML][HTML] Why do G-quadruplexes dimerize through the 5'-ends? Driving forces for G4 DNA dimerization examined in atomic detail
M Kogut, C Kleist, J Czub - PLoS computational biology, 2019 - journals.plos.org
G-quadruplexes (G4) are secondary structures formed by guanine-rich nucleic acid
sequences and shown to exist in living cells where they participate in regulation of gene …
sequences and shown to exist in living cells where they participate in regulation of gene …
A direct view of the complex multi-pathway folding of telomeric G-quadruplexes
M Aznauryan, S Søndergaard, SL Noer… - Nucleic Acids …, 2016 - academic.oup.com
Abstract G-quadruplexes (G4s) are DNA secondary structures that are capable of forming
and function in vivo. The propensity of G4s to exhibit extreme polymorphism and complex …
and function in vivo. The propensity of G4s to exhibit extreme polymorphism and complex …
Insight into G-DNA structural polymorphism and folding from sequence and loop connectivity through free energy analysis
X Cang, J Sponer, TE Cheatham, III - Journal of the American …, 2011 - ACS Publications
The lengths of G-tracts and their connecting loop sequences determine G-quadruplex
folding and stability. Complete understanding of the sequence–structure relationships …
folding and stability. Complete understanding of the sequence–structure relationships …
Folding kinetics of G-quadruplexes: Duplex stem loops drive and accelerate G-quadruplex folding
TQN Nguyen, KW Lim, AT Phan - The Journal of Physical …, 2020 - ACS Publications
The folding kinetics is an important parameter affecting the relevance of DNA and RNA G-
quadruplex (G4) structures in biological processes. Previous studies of the G4 folding …
quadruplex (G4) structures in biological processes. Previous studies of the G4 folding …