Malaria is a major global threat, that results in more than 2 million deaths each year. The
treatment of malaria is becoming extremely difficult due to the emergence of drug-resistant …

Malaria with one million deaths and about 500 million new cases reported annually is a
challenge to drug therapy and discovery. As current antimalarial therapeutics become …

Malaria continues to plague the tropical and subtropical regions causing high morbidity and
mortality. Every year, millions die due to lack of affordable and effective anti-malarial drugs …

Malaria remains a major health problem, especially because of the emergence of resistant
P. falciparum strains to artemisinin derivatives. In this context, safe and affordable …

The emergence and spread of drug-resistant malaria parasites is a serious public health
problem in the tropical world. Malaria control has relied upon the traditional quinoline …

Major advances in our understanding of malaria parasite biology have been made. Coupled
with the completion of the malaria genome, this has presented exciting opportunities for …

Malaria elimination has recently been reinstated as a global health priority but current
therapies seem to be insufficient for the task. Elimination efforts require new drug classes …

Drugs represent the primary treatment available for human malaria, as caused by
Plasmodium spp. Currently approved drugs and antimalarial drug leads generally work …

The malaria parasite resistance to the existing drugs is a serious problem to the currently
used antimalarials and, thus, highlights the urgent need to develop new and effective anti …

New antimalarial compounds with novel mechanisms of action are urgently needed to
combat the recent rise in antimalarial drug resistance. Phenotypic high-throughput screens …