The double-edged role of hydrogen sulfide in the pathomechanism of multiple liver diseases

B Liu, S Wang, M Xu, Y Ma, R Sun, H Ding… - Frontiers in …, 2022 - frontiersin.org
In mammalian systems, hydrogen sulfide (H2S)—one of the three known gaseous signaling
molecules in mammals—has been found to have a variety of physiological functions …

Fluorescent probes for hydrogen sulfide detection

B Peng, M Xian - Asian Journal of Organic Chemistry, 2014 - Wiley Online Library
Hydrogen sulfide (H2S) is an important signaling molecule with potent cytoprotective
actions. Current results strongly suggest that modulation of H2S levels could have potential …

Exogenous hydrogen sulfide regulates the growth of human thyroid carcinoma cells

D Wu, J Li, Q Zhang, W Tian, P Zhong… - Oxidative Medicine …, 2019 - Wiley Online Library
Hydrogen sulfide (H2S) is involved in the development and progression of many types of
cancer. However, the effect and mechanism of H2S on the growth of human thyroid …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

The therapeutic potential of hydrogen sulfide: separating hype from hope

KR Olson - American Journal of Physiology-Regulatory …, 2011 - journals.physiology.org
Hydrogen sulfide (H2S) has become the hot new signaling molecule that seemingly affects
all organ systems and biological processes in which it has been investigated. It has also …

Hydrogen sulfide and functional therapy: novel mechanisms from epigenetics

Q Ding, W Song, M Zhu, Y Yu, Z Lin, W Hu… - Antioxidants & Redox …, 2024 - liebertpub.com
Hydrogen sulfide (H2S) is a gasotransmitter with significant physiological effects, including
anti-inflammatory properties, regulation of oxidative stress, and vasodilation, thus regulating …

Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

C Szabo, C Coletta, C Chao, K Módis… - Proceedings of the …, 2013 - National Acad Sciences
The physiological functions of hydrogen sulfide (H2S) include vasorelaxation, stimulation of
cellular bioenergetics, and promotion of angiogenesis. Analysis of human colon cancer …

Therapeutic potential of endogenous hydrogen sulfide inhibition in breast cancer

M Li, Y Liu, Y Deng, L Pan, H Fu, X Han… - Oncology …, 2021 - spandidos-publications.com
Abstract Hydrogen sulfide (H 2 S), the third gas signal molecule, is associated with the
modulation of various physiological and pathological processes. Recent studies have …

Hydrogen sulfide as a therapeutic target for inflammation

JR Rivers, A Badiei, M Bhatia - Expert opinion on therapeutic …, 2012 - Taylor & Francis
Introduction: The view of hydrogen sulfide has changed from a toxic by-product to a crucial
signaling molecule, with enormous potential as a pharmacological target for diseases …

H2S metabolism in colon cancer cells: Effect of hypoxia

F Malagrinò, K Zuhra, D Mastronicola, L Mascolo… - Free Radical Biology …, 2018 - Elsevier
Hydrogen sulfide (H 2 S) plays key roles in human (patho) physiology. Synthesized
endogenously by known enzymatic systems, H 2 S is mainly metabolized through a …