After spinal cord injury (SCI), about 50% of the oligodendrocytes and astrocytes in the
residual white matter at the injury site are lost by 24 h. However, chronically after SCI, the …

Given the numerous reparative roles glia may play after spinal cord injury (SCI), glial
proliferation and cell number were examined in a model of traumatic SCI. Emphasis was …

Studies in the rat have shown that contusive spinal cord injury (SCI) results in devastating
pathology, including significant loss of mature oligodendrocytes and astrocytes even in …

Oligodendrocyte (OL) loss and axon demyelination occur after spinal cord injury (SCI). OLs
may be replaced, however, by proliferating NG2+ progenitor cells. Indeed, new OLs have …

The reaction of oligodendrocyte progenitor cells (OPCs) after spinal cord injury (SCI) is
poorly understood. In this study, we examined oligodendroglial reactions after contusion SCI …

Astrocytes and their precursors respond to spinal cord injury (SCI) by proliferating, migrating,
and altering phenotype. This contributes to glial scar formation at the lesion border and …

Spinal cord injury (SCI) involves the loss of neurons and glia due to initial mechanical and
secondary biochemical mechanisms. Treatment with the sodium channel blocker …

Numerous efforts have been made to maximize the efficacy of treatment for spinal cord injury
(SCI). Recently, oligodendrocyte-type 2 astrocyte (O-2A) progenitor cells have been …

The adult mammalian spinal cord contains neural stem and/or progenitor cells that slowly
multiply throughout life and differentiate exclusively into glia. The contribution of adult …

Spontaneous remyelination occurs after spinal cord injury (SCI), but the extent of myelin
repair and identity of the cells responsible remain incompletely understood and contentious …