Early detection of late-onset sepsis (LOS) in preterm infants is crucial since timely treatment
initiation is a key prognostic factor. We hypothesized that fecal volatile organic compounds …

Objectives: Several studies associated altered gut microbiota composition in preterm infants
with late-onset sepsis (LOS), up to days before clinical onset of sepsis. Microbiota analysis …

Background The intestinal microbiota has increasingly been considered to play a role in the
etiology of late-onset sepsis (LOS). We hypothesize that early alterations in fecal volatile …

Introduction: Although the exact pathophysiological mechanisms of both necrotizing
enterocolitis (NEC) and late-onset sepsis (LOS) in preterm infants are yet to be elucidated …

Background Late onset sepsis (LOS) in preterm infants is associated with considerable
morbidity and mortality. While studies have implicated gut bacteria in the aetiology of the …

Background: Late onset sepsis (LOS) in preterm infants is preceded by fecal volatile organic
compound (VOC) alterations, suggesting an etiologic role of gut microbiota in LOS rather …

Objective The fecal microbiota and metabolome are hypothesized to be altered before late-
onset neonatal meningitis (LOM), in analogy to late-onset sepsis (LOS). The present study …

Fecal volatile organic compounds (VOC) reflect human and gut microbiota metabolic
pathways and their interaction. VOC behold potential as non-invasive preclinical diagnostic …

Background Gut dysbiosis has been suggested as a major risk factor for the development of
late-onset sepsis (LOS), a main cause of mortality and morbidity in preterm infants. We …

Although late-onset sepsis (LOS) is a major cause of neonatal morbidity and mortality,
biomarkers evaluated in LOS lack high diagnostic accuracy. In this prospective, case …