It has been acknowledged that oxidative stress, resulting in the apoptosis of dopaminergic
neurons, is a key mechanism in the pathogenesis of Parkinson's disease (PD). Puerarin …

Neurodegeneration is one of the primary etiologies in the onset of Parkinson's disease. In
the quest for a new antiparkinsonism treatment the potential benefits of puerarin from the …

The aim of this study was to investigate Parkinson's disease (PD) using a murine model of
PD. Specifically, we aimed to explore the mechanism by which puerarin prevents …

Puerarin, an active component of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep
is well‐known for its anti‐oxidative and neuroprotective activities. Although anti‐Parkinson's …

Background Parkinson's disease (PD) is manifested as degeneration of dopaminergic
neurons in substantia nigra compacta. The mitochondrial dysfunction induced by oxidative …

Background Parkinson's disease (PD) is caused by the gradual loss of dopamine-producing
cells in the brain. This study evaluated the potential neuroprotective role of puerarin (PR) on …

In the present study, we aimed to investigate the protective effect of puerarin (PR) on the
substantia nigra (SN) of 6-hydroxydopamine (6-OHDA)-lesioned rats. Our results show that …

In this study, we hypothesized that anti-parkinsonian effect of puerarin is attributable to its
antioxidant properties via Nrf2-dependent glutathione (GSH) biosynthesis mechanism …

An increasing number of studies suggest that oxidative stress is associated with the
Parkinsonian process. This study evaluated the potential neuroprotective role of puerarin …

Puerarin is an isoflavone compound derived from Pueraria lobata in traditional Chinese
medicine. Accumulating evidence has indicated that puerarin demonstrates multiple …