Cardiac output, peak systolic pressure, and heart rate were reduced and left ventricular end-
diastolic pressure was increased in 10 animals following 1 hour of normothermic aortic cross …

Myocardial protection has become an essential adjunctive measure in cardiac surgery for a
couple of decades, because since the 1950s, the methods of cardioprotection (cardioplegic …

The modalities of 25 mEq. per liter potassium-induced arrest in a simulated extracellular
fluid, and 15° C. perfusion hypothermia were combined and used exclusively for myocardial …

During open-heart operations, periods occur during which the blood supply to the heart is
stopped. Myocardial damage can be limited by cooling and induction of electromechanical …

Seventeen of 34 consecutive patients undergoing coronary artery bypass grafting were
randomly assigned to one of two methods of myocardial preservation. With the cold …

To evaluate the importance of time, temperature, and cardioplegia on the ability of the
canine myocardium to maintain functional and ultrastructural integrity following induced …

Hypothermia induced at the onset of ischemia is a potent experimental cardioprotective
strategy for myocardial infarction. The aim of our study was to determine whether the …

Effective protection against the consequences of transient myocardial ischaemia requires a
consideration of events not only during the ischaemic interval but also during the pre-and …

In many animal models, mild therapeutic hypothermia is a powerful intervention, reducing
myocardial infarct size, reducing the no-reflow phenomenon, and improving healing after …

The aim of this study was to determine the temperature for optimal myocardial preservation
during cardioplegic arrest. In isolated canine hearts perfused by a support dog, functional …