Aims Ischemic stroke is one of the leading causes of death worldwide and the most common
cause of disability in Western countries. Multiple mechanisms contribute to the development …

After ischemic stroke, the integrity of the blood-brain barrier is compromised. Peripheral
immune cells, including neutrophils, T cells, B cells, dendritic cells, and macrophages …

Through considerable effort in research and clinical studies, the immune system has been
identified as a participant in the onset and progression of brain injury after ischaemic stroke …

Ischemic stroke accounts for the majority of stroke cases and constitutes a major cause of
death and disability in the industrialized world. Inflammation has been reported to constitute …

Background and Purpose The most common strategy for treating patients with acute
ischemic stroke is thrombolytic therapy, though only a few patients receive benefits because …

Ischemic stroke is a leading cause of disability and death. It imposes a heavy economic
burden on individuals, families and society. The mortality rate of ischemic stroke has …

Despite considerable efforts in research and clinical studies, stroke is still one of the leading
causes of death and disability worldwide. Originally, stroke was considered a vascular …

Stroke accounts for a large proportion of morbidity and mortality burden in China. Moreover,
there is a high prevalence of the leading risk factors for stroke, including hypertension and …

Stroke represents the most frequent cause of permanent disability in adults worldwide.
Cerebral ischemia triggers the pathological pathways of the ischemic cascade and causes …

The immune system is rapidly activated after ischemic stroke. As immune cells migrate and
infiltrate across the blood-brain barrier into the ischemic region, a cascade of cellular and …