Blood cell-derived RANTES mediates cerebral microvascular dysfunction, inflammation, and tissue injury after focal ischemia–reperfusion

S Terao, G Yilmaz, KY Stokes, J Russell, M Ishikawa… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Although chemokines have been implicated in cardiovascular
diseases, few studies have addressed the role of these inflammatory mediators in ischemic …

The spleen may be an important target of stem cell therapy for stroke

Z Wang, D He, YY Zeng, L Zhu, C Yang, YJ Lu… - Journal of …, 2019 - Springer
Stroke is the most common cerebrovascular disease, the second leading cause of death
behind heart disease and is a major cause of long-term disability worldwide. Currently …

Emerging targets for modulation of immune response and inflammation in stroke

K Thapa, K Shivam, H Khan, A Kaur, K Dua… - Neurochemical …, 2023 - Springer
The inflammatory and immunological responses play a significant role after stroke. The
innate immune activation stimulated by microglia during stroke results in the migration of …

Glial cells: role of the immune response in ischemic stroke

S Xu, J Lu, A Shao, JH Zhang, J Zhang - Frontiers in immunology, 2020 - frontiersin.org
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …

[HTML][HTML] Protective features of peripheral monocytes/macrophages in stroke

M Gliem, M Schwaninger, S Jander - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Hematogenous recruitment of monocytes and macrophages has traditionally been viewed
as a harmful process causing exacerbation of brain injury after stroke. However, emerging …

Inflammatory responses after ischemic stroke

JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

[HTML][HTML] Cytokines: their role in stroke and potential use as biomarkers and therapeutic targets

DN Doll, TL Barr, JW Simpkins - Aging and disease, 2014 - ncbi.nlm.nih.gov
Inflammatory mechanisms both in the periphery and in the CNS are important in the
pathophysiologic processes occurring after the onset of ischemic stroke (IS). Cytokines are …

Inflammation as therapeutic objective in stroke

J Jordán, T Segura, D Brea… - Current …, 2008 - ingentaconnect.com
Ischemic stroke is the most frequent cause of persistent neurologic disability in modern
Western societies. Albeit it is still not clear whether inflammation is merely an …

Immune and inflammatory responses to stroke: good or bad?

PA McCombe, SJ Read - International Journal of Stroke, 2008 - journals.sagepub.com
Inflammatory and immune responses play important roles following ischaemic stroke.
Inflammatory responses contribute to damage and also contribute to repair. Injury to tissue …

Interleukins and ischemic stroke

H Zhu, S Hu, Y Li, Y Sun, X Xiong, X Hu… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability
worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information …