[HTML][HTML] The prognostic value of serum cytokines in patients with acute ischemic stroke

X Li, S Lin, X Chen, W Huang, Q Li, H Zhang… - Aging and …, 2019 - ncbi.nlm.nih.gov
The inflammatory response is an unavoidable process and contributes to the destruction of
cerebral tissue during the acute ischemic stroke (AIS) phase and has not been addressed …

Thrombosis, neuroinflammation, and poststroke infection: the multifaceted role of neutrophils in stroke

J Ruhnau, J Schulze, A Dressel… - Journal of immunology …, 2017 - Wiley Online Library
Immune cells can significantly predict and affect the clinical outcome of stroke. In particular,
the neutrophil‐to‐lymphocyte ratio was shown to predict hemorrhagic transformation and the …

New insight into neutrophils: a potential therapeutic target for cerebral ischemia

R Chen, X Zhang, L Gu, H Zhu, Y Zhong, Y Ye… - Frontiers in …, 2021 - frontiersin.org
Ischemic stroke is one of the main issues threatening human health worldwide, and it is also
the main cause of permanent disability in adults. Energy consumption and hypoxia after …

Immune cells after ischemic stroke onset: roles, migration, and target intervention

L Ao, YY Yan, L Zhou, C Li, WT Li, W Fang… - Journal of Molecular …, 2018 - Springer
Ischemic stroke is one of the leading health issues and the major cause of permanent
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …

Thrombo-inflammation and immunological response in ischemic stroke: focusing on platelet-tregs interaction

J Cui, H Li, Z Chen, T Dong, X He, Y Wei… - Frontiers in Cellular …, 2022 - frontiersin.org
Strokes are mainly caused by thromboembolic obstruction of a major cerebral artery. Major
clinical manifestations include paralysis hemiplegia, aphasia, memory, and learning …

Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA

N Kostulas, P Kivisäkk, Y Huang, D Matusevicius… - Stroke, 1998 - Am Heart Assoc
Background and Purpose—Ischemic brain injury secondary to an arterial occlusion is
characterized by acute local inflammation. Blood polymorphonuclear leukocytes (PMNL) …

Reparative system arising from CCR2 (+) monocyte conversion attenuates neuroinflammation following ischemic stroke

J Park, JY Kim, YR Kim, M Huang, JY Chang… - Translational Stroke …, 2021 - Springer
Monocytes recruitment from the blood to inflamed tissues following ischemic stroke is an
important immune response to wound healing and tissue repair. Mouse monocytes can be …

T cell response in ischemic stroke: from mechanisms to translational insights

D Zhang, J Ren, Y Luo, Q He, R Zhao, J Chang… - Frontiers in …, 2021 - frontiersin.org
Ischemic stroke, caused by a sudden disruption of blood flow to the brain, is a leading cause
of death and exerts a heavy burden on both patients and public health systems. Currently …

Neuroinflammation in post-ischemic neurodegeneration of the brain: friend, foe, or both?

R Pluta, S Januszewski, SJ Czuczwar - International Journal of Molecular …, 2021 - mdpi.com
One of the leading causes of neurological mortality, disability, and dementia worldwide is
cerebral ischemia. Among the many pathological phenomena, the immune system plays an …

Update on inflammatory biomarkers and treatments in ischemic stroke

A Bonaventura, L Liberale, A Vecchié… - International journal of …, 2016 - mdpi.com
After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly
induce both beneficial and detrimental effects. In this narrative review, we updated evidence …